Department of Biochemistry and Molecular Biology, Molecular Cell Biology Program, Plant Biology Program, University of Massachusetts, Amherst, Massachusetts 01003, USA.
Department of Biology, Penn State University, University Park, Pennsylvania 16802, USA.
Plant Cell. 2022 Jan 20;34(1):53-71. doi: 10.1093/plcell/koab234.
The field of plant cell biology has a rich history of discovery, going back to Robert Hooke's discovery of cells themselves. The development of microscopes and preparation techniques has allowed for the visualization of subcellular structures, and the use of protein biochemistry, genetics, and molecular biology has enabled the identification of proteins and mechanisms that regulate key cellular processes. In this review, seven senior plant cell biologists reflect on the development of this research field in the past decades, including the foundational contributions that their teams have made to our rich, current insights into cell biology. Topics covered include signaling and cell morphogenesis, membrane trafficking, cytokinesis, cytoskeletal regulation, and cell wall biology. In addition, these scientists illustrate the pathways to discovery in this exciting research field.
植物细胞生物学领域有着丰富的发现历史,可以追溯到罗伯特·胡克发现细胞本身。显微镜和制备技术的发展使人们能够观察到亚细胞结构,而蛋白质生物化学、遗传学和分子生物学的应用使人们能够识别调节关键细胞过程的蛋白质和机制。在这篇综述中,七位资深植物细胞生物学家回顾了过去几十年中这一研究领域的发展,包括他们的团队为我们目前对细胞生物学的丰富见解所做出的基础性贡献。所涵盖的主题包括信号转导和细胞形态发生、膜运输、胞质分裂、细胞骨架调节和细胞壁生物学。此外,这些科学家还展示了在这个令人兴奋的研究领域中发现的途径。