Qureshi Mehak, Abdelazeem Basel, Khan Ashiya, Najjar Mazen
McLaren Health Care, Flint/Michigan State University, Flint, Michigan, USA.
Eur J Case Rep Intern Med. 2021 Aug 9;8(8):002755. doi: 10.12890/2021_002755. eCollection 2021.
is an encapsulated, yeast-like fungus that commonly lives in the environment due to soil contamination by the faeces of birds, especially pigeons. Cryptococcus is an opportunistic fungal infection frequently diagnosed in immunocompromised patients with HIV, steroid use, malignancy, history of organ transplantation, or, rarely, sarcoidosis. There have been only a few reports of cryptococcus infection in sarcoidosis patients who were not on steroid treatment. Here, we highlight the importance of considering opportunistic fungal infection in asymptomatic treatment-naive sarcoidosis patients. We present a patient with a history of asymptomatic, treatment-naive sarcoidosis who presented with headache and was diagnosed with cryptococcal meningitis in the presence of an idiopathic T-cell lymphopenia.
Cryptococcus is an opportunistic fungal infection commonly diagnosed in immunocompromised patients.Sarcoidosis is a multi-systemic disease characterized by the formation of granulomas in various organs, most commonly found in the lungs and mediastinal lymph nodes.
隐球菌是一种有包膜的酵母样真菌，由于鸟类尤其是鸽子的粪便污染土壤，它通常存在于环境中。隐球菌是一种机会性真菌感染，常见于免疫功能低下的患者，如感染人类免疫缺陷病毒（HIV）者、使用类固醇者、恶性肿瘤患者、有器官移植史者，或很少见的结节病患者。关于未接受类固醇治疗的结节病患者发生隐球菌感染的报道仅有几例。在此，我们强调在无症状且未接受过治疗的结节病患者中考虑机会性真菌感染的重要性。我们报告一名有无症状、未接受过治疗的结节病病史的患者，该患者出现头痛，在存在特发性T细胞淋巴细胞减少的情况下被诊断为隐球菌性脑膜炎。
隐球菌是一种常见于免疫功能低下患者的机会性真菌感染。结节病是一种多系统疾病，其特征是在各个器官形成肉芽肿，最常见于肺部和纵隔淋巴结。
