Research & Development Centre, Bharathiyar University, Coimbatore, Tamil Nadu, India.
Department of Radiation Oncology, The Medicity, Gurugram, Haryana, India.
J Cancer Res Ther. 2021 Jul-Sep;17(4):870-874. doi: 10.4103/jcrt.JCRT_962_20.
The aim of this study was to measure and compare the output factor (OF) of a CyberKnife Robotic Radiosurgery System with eight different small field detectors and validate with Technical Report Series (TRS) report 483.
Accurate dosimetry of CyberKnife system is limited due to the challenges in small field dosimetry. OF is a vital dosimetric parameter used in the photon beam modeling and any error would affect the dose calculation accuracy.
In this study, the OF was measured with eight different small-field detectors for the 12 IRIS collimators at 800 mm SAD setup at 15 mm depth. The detectors used were PTW 31016 PinPoint 3D, IBA PFD shielded diode, IBA EFD unshielded diode, IBA SFD unshielded diode (stereotactic), PTW 60008 shielded diode, PTW 60012 unshielded diode, PTW 60018 unshielded diode (stereotactic), and PTW 60019 CVD diamond detector. OF was obtained after correcting for field output correction factors from IAEA TRS No. 483.
The field OFs in CyberKnife are derived from the measured data by applying the correction factors from Table 23 in TRS 483 for the eight small field detectors. These field OFs matched within 2% of peer-reviewed published values. The range and standard deviation showed a decreasing trend with collimator diameter.
The field OF obtained after applying the appropriate correction factor from TRS 483 matched well with the peer-reviewed published OFs. The inter-detector variation showed a decreasing trend with increasing collimator field size. This study gives physicists confidence in measuring field OFs while using small field detectors mentioned in this work.
本研究旨在测量和比较 CyberKnife 机器人放射外科系统的输出因子(OF)与八种不同的小场探测器,并与技术报告系列(TRS)报告 483 进行验证。
由于在小场剂量学方面存在挑战,CyberKnife 系统的精确剂量测定受到限制。OF 是光子束建模中一个重要的剂量学参数,任何误差都会影响剂量计算的准确性。
在这项研究中,在 800mm SAD 设置下,于 15mm 深度处,使用八种不同的小场探测器对 12 个 IRIS 准直器的 OF 进行了测量。所使用的探测器包括 PTW 31016 PinPoint 3D、IBA PFD 屏蔽二极管、IBA EFD 非屏蔽二极管、IBA SFD 非屏蔽二极管(立体定向)、PTW 60008 屏蔽二极管、PTW 60012 非屏蔽二极管、PTW 60018 非屏蔽二极管(立体定向)和 PTW 60019 CVD 金刚石探测器。OF 是在从 IAEA TRS No.483 获得的场输出校正因子校正后得到的。
CyberKnife 的场 OF 是通过应用 TRS 483 表 23 中的校正因子从测量数据中得出的,适用于这八种小场探测器。这些场 OF 在 2%以内与经过同行评审的已发表值相匹配。随着准直器直径的减小,范围和标准偏差呈现出下降的趋势。
应用 TRS 483 中的适当校正因子后获得的场 OF 与经过同行评审的已发表 OF 吻合良好。随着准直器场尺寸的增大,探测器之间的差异呈现出减小的趋势。本研究使物理学家有信心在使用本文中提到的小场探测器测量场 OF 时。