Departamento de Urologia, Universidade do Estado do Rio de Janeiro - UERJ, Rio de Janeiro, RJ, Brasil.
Int Braz J Urol. 2022 Jan-Feb;48(1):110-119. doi: 10.1590/S1677-5538.IBJU.2021.0424.
Nephrometric scores play an interesting role in nephron sparring surgery (NSS) planning. The aim of this study is to evaluate if R.E.N.A.L. score (RS) is capable to predict the occurrence of adverse events in laparoscopic NSS.
We prospectively studied 150 laparoscopic NSS between 2015 and 2018 to evaluate the relationship between RS and incidence of adverse events. Clavien 3 or superior complications, warm ischemia time (WIT) over 30 minutes, tumor violation, positive surgical margins (PSM) and necessity of amplification of renal parenchyma during the resection of the masses to obtain free margins were considered as adverse events. We compared each item of the RS isolated and divided the patients between low risk and high risk.
Adverse results occurred in 48 cases (32%). Amplification of the margin of resection was observed in 28 cases (19%). WIT exceeded 30 minutes in 9 cases (6.1%), complications Clavien 3 or superior occurred in 13 cases (9%) and PSM were detected en 6 cases (4%). Comparing the patients with adverse outcomes and each item of the RS we did not find any statistical difference, but when divided into high risk and low risk, we found that patients in the high risk group had a higher tendency to present ad-verse results - 25.84% vs. 44.26% (p=0.03).
RS system is a good way to predict adverse outcomes in NSS, especially in cases over 7. Further studies should focus on robotic approach and patient's characteristics other than the masses' aspects.
肾测量评分在保肾手术(NSS)规划中具有重要作用。本研究旨在评估 R.E.N.A.L. 评分(RS)是否能够预测腹腔镜 NSS 中不良事件的发生。
我们前瞻性研究了 2015 年至 2018 年间进行的 150 例腹腔镜 NSS,以评估 RS 与不良事件发生率之间的关系。Clavien 3 级或更高级别的并发症、热缺血时间(WIT)超过 30 分钟、肿瘤侵犯、阳性手术切缘(PSM)以及为获得无肿瘤边缘而需要扩大肾实质切除范围被视为不良事件。我们比较了 RS 孤立的每个项目,并将患者分为低危和高危组。
48 例(32%)出现不良结果。28 例(19%)需要扩大切除边缘。9 例(6.1%)WIT 超过 30 分钟,13 例(9%)发生 Clavien 3 级或更高级别的并发症,6 例(4%)检测到 PSM。比较有不良结果的患者和 RS 的每个项目,我们没有发现任何统计学差异,但当分为高危和低危组时,我们发现高危组患者出现不良结果的倾向更高——25.84%对 44.26%(p=0.03)。
RS 系统是预测 NSS 不良结果的一种较好方法,尤其是在超过 7 分的病例中。进一步的研究应侧重于机器人手术方法和患者特征,而不仅仅是肿瘤方面。