Zhang X H, Wu W X, Li Y H, Cui J F
Department of Pathology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Zhonghua Zhong Liu Za Zhi. 2021 Sep 23;43(9):906-911. doi: 10.3760/cma.j.cn112152-20200409-00324.
Appendiceal epithelial neoplasms including benign and malignant, are clinically rare. There were quite a lot of changings in classification systems for them and different pathological diagnostic terminologies were used, resulted in confusions of understanding and communication for both pathologists and clinicians. Basically, appendiceal epithelial neoplasms include adenoma, serrated lesion and polyps, mucinous neoplasms, carcinoma and neuroendocrine neoplasms. Appendiceal mucinous neoplasms and goblet cell carcinoma are exclusively seen in the appendix. Though some appendiceal neoplasms are similar to those in large bowl, however, the molecular mechanism is different. The classification, pathological diagnosis and clinical significance of appendiceal epithelial neoplasms were summarized based on the fifth edition of WHO classification on digestive system tumors and other related literatures.
包括良性和恶性的阑尾上皮性肿瘤在临床上较为罕见。其分类系统有诸多变化，使用了不同的病理诊断术语，这导致病理学家和临床医生在理解和交流上产生困惑。基本上，阑尾上皮性肿瘤包括腺瘤、锯齿状病变和息肉、黏液性肿瘤、癌和神经内分泌肿瘤。阑尾黏液性肿瘤和杯状细胞癌仅见于阑尾。尽管一些阑尾肿瘤与大肠肿瘤相似，但其分子机制不同。基于世界卫生组织消化系统肿瘤分类第五版及其他相关文献，对阑尾上皮性肿瘤的分类、病理诊断及临床意义进行了总结。
