Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, London, UK.
Van Yuzuncu yil Hospital, Department of Cardiology, Van, Turkey.
Cardiol Young. 2022 May;32(5):824-826. doi: 10.1017/S1047951121003838. Epub 2021 Sep 17.
Allergic reactions related to drug use is a common entity presenting often from minor urticaria to life-threatening anaphylactoid reactions. A common but easily overlooked diagnosis, Kounis syndrome, is an established hypersensitivity coronary disorder induced by drugs, foods, environmental factors, and coronary stents that can present in the same way as non-allergy-induced acute coronary syndrome. Here within, we present a unique case of dual presentation of Kounis syndrome and prolonged QTc in a young patient after a single dose of Domperidone and Lansoprazole.
与药物使用相关的过敏反应是一种常见的实体,通常表现为轻度荨麻疹到危及生命的类过敏反应。Kounis 综合征是一种常见但容易被忽视的诊断,它是一种由药物、食物、环境因素和冠状动脉支架引起的已确立的过敏敏感性冠状动脉疾病,其表现方式与非过敏引起的急性冠状动脉综合征相同。在这里,我们介绍了一例年轻患者单次使用多潘立酮和兰索拉唑后同时出现 Kounis 综合征和 QTc 延长的独特病例。