From the Department of Medicine, Jersey Shore University Medical Center, Neptune, NJ.
Department of Allergy and Immunology, Jersey Shore University Medical Center, Neptune, NJ.
Cardiol Rev. 2023;31(4):230-232. doi: 10.1097/CRD.0000000000000436. Epub 2022 Jan 6.
Kounis syndrome is a hypersensitivity disorder secondary to allergy or anaphylaxis that can result in acute coronary syndrome. Kounis syndrome has an increasing prevalence since its first identification in 1950. Divided into 3 subtypes, each with diagnostic criteria, the management of Kounis syndrome presents a clinical challenge. We aim to identify the pathophysiological mechanisms and review the diagnosis, epidemiology, management strategies, and future directions of Kounis syndrome. As Kounis syndrome becomes more widely recognized in the medical community, the role of diagnosis, treatment, and future immunomodulatory prevention strategies will continue to unfold.
库恩斯综合征是一种由过敏或过敏反应引起的超敏反应障碍，可导致急性冠状动脉综合征。自 1950 年首次发现以来，库恩斯综合征的发病率呈上升趋势。库恩斯综合征分为 3 个亚型，每个亚型都有诊断标准，其管理具有临床挑战性。我们旨在确定库恩斯综合征的病理生理机制，并回顾其诊断、流行病学、管理策略和未来方向。随着库恩斯综合征在医学界得到更广泛的认可，诊断、治疗和未来免疫调节预防策略的作用将不断显现。
