Blandin G, Fargetton B, Latil F
Allerg Immunol (Paris). 1987 Apr;19(4):143-8.
Isocyanates are often used in making polyurethanes (foam, varnish, paint, glue). They interest allergists and work physicians. Effects are different according to concentration. In strong concentration they are irritant. In weak concentration they bring on asthma. A long exposure may provoke chronic airway obstruction. Diagnosis is not easy, based on clinical, physiologic and laboratory characteristics. Mechanism is unknown (immunological, irritant, beta-blocking effect).
异氰酸酯常用于制造聚氨酯（泡沫、清漆、涂料、胶水）。它们引起过敏症专科医生和职业医生的关注。根据浓度不同，其影响也不同。高浓度时具有刺激性。低浓度时会引发哮喘。长期接触可能导致慢性气道阻塞。基于临床、生理和实验室特征进行诊断并不容易。作用机制尚不清楚（免疫、刺激、β受体阻滞效应）。
