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生姜提取物、天然蜂蜜和苦巧克力是否像含氟牙膏一样使牙釉质再矿化?一项研究。

Do Ginger Extract, Natural Honey and Bitter Chocolate Remineralize Enamel Surface as Fluoride Toothpastes? An Study.

机构信息

VM Medical Park Bursa Hospital, Dental Clinic, Private Practice, Bursa, Turkey.

KidSmile Dental Clinic, Private Practice, Istanbul, Turkey.

出版信息

Niger J Clin Pract. 2021 Sep;24(9):1283-1288. doi: 10.4103/njcp.njcp_683_20.

Abstract

BACKGROUND

In recent literatures, much attention has been given to natural products for their health benefits.

AIMS

In this study, the objective was to measure the efficacy of the ginger-honey-chocolate mixture as the remineralization effect has been shown in the literature previously and to evaluate the individual contributions of this mixture; ginger, natural honey, bitter chocolate separately on remineralization of initial enamel caries lesion.

MATERIALS AND METHODS

All specimens were divided into eight groups as: Ginger (Arifoglu®, Turkey) in powder form, (n = 8); Ginger-Honey-Chocolate (n = 8); Natural honey (Balparmak Plateau Blossom Honey®, Turkey) (n = 9); Bitter chocolate (Nestlé®, Switzerland) (n = 8); MI Paste (GC, Japan) (n = 8); Paradontax (Sensodyne, Glaxosmithklein, USA) (n = 9); Pronamel (Sensodyne, Glaxosmithklein, USA) (n = 9); Control (n = 9) groups. Samples were carried out five pH cycles along 7 days at 37°C for each group. During pH cycling, blocks were put in a demineralization (6 h) and a remineralization solution (18 h). The treatment consisted of 1 min. interaction of enamel surfaces with agent/deionized slurries (1:3 w/w) on a daily basis. The surface microhardness (SMH) was determined before and after pH cycling with a Digital Micro-Vickers Hardness Tester (Wilson Wolpert; Europe BV, 401 MVD, Netherlands). Mineral changes were determined by using FluoreCam® and recovery values were calculated as SMHR% and FΔ%, respectively.

RESULTS

All groups showed an enhanced remineralization. There was no significant difference in terms of FΔ% (F = 1.223, P = 0.304) and SMHR% (F = 0.709, P = 0.664) between all groups.

CONCLUSION

The herbals (ginger, honey, and bitter chocolate) examined in this study gave promising results with a high remineralization potential.

摘要

背景

在最近的文献中,人们对天然产物的健康益处给予了极大关注。

目的

本研究旨在测量姜-蜜-巧克力混合物的功效,因为之前的文献已经证明了这种混合物具有再矿化作用,并评估这种混合物、姜、天然蜂蜜、苦巧克力单独对初始釉质龋损再矿化的作用。

材料和方法

所有标本均分为八组:姜(土耳其的 Arifoglu®)粉末形式(n = 8);姜-蜜-巧克力(n = 8);天然蜂蜜(土耳其的 Balparmak Plateau Blossom Honey®)(n = 9);苦巧克力(瑞士的 Nestlé®)(n = 8);MI Paste(GC,日本)(n = 8);Paradontax(Sensodyne,Glaxosmithklein,美国)(n = 9);Pronamel(Sensodyne,Glaxosmithklein,美国)(n = 9);对照组(n = 9)。每个组在 37°C 下进行 7 天 5 个 pH 循环。在 pH 循环过程中,将样本在脱矿化(6 h)和再矿化溶液(18 h)中放置。处理方法是每天将牙釉质表面与试剂/去离子浆料(1:3 w/w)接触 1 分钟。用数字显微维氏硬度计(Wilson Wolpert;欧洲 BV,401 MVD,荷兰)在 pH 循环前后测定表面显微硬度(SMH)。用 FluoreCam®测定矿物质变化,并分别计算恢复值作为 SMHR%和 FΔ%。

结果

所有组均表现出增强的再矿化作用。所有组之间的 FΔ%(F = 1.223,P = 0.304)和 SMHR%(F = 0.709,P = 0.664)差异均无统计学意义。

结论

本研究中检查的草药(姜、蜂蜜和苦巧克力)具有很高的再矿化潜力,结果令人鼓舞。

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