VM Medical Park Bursa Hospital, Dental Clinic, Private Practice, Bursa, Turkey.
KidSmile Dental Clinic, Private Practice, Istanbul, Turkey.
Niger J Clin Pract. 2021 Sep;24(9):1283-1288. doi: 10.4103/njcp.njcp_683_20.
In recent literatures, much attention has been given to natural products for their health benefits.
In this study, the objective was to measure the efficacy of the ginger-honey-chocolate mixture as the remineralization effect has been shown in the literature previously and to evaluate the individual contributions of this mixture; ginger, natural honey, bitter chocolate separately on remineralization of initial enamel caries lesion.
All specimens were divided into eight groups as: Ginger (Arifoglu®, Turkey) in powder form, (n = 8); Ginger-Honey-Chocolate (n = 8); Natural honey (Balparmak Plateau Blossom Honey®, Turkey) (n = 9); Bitter chocolate (Nestlé®, Switzerland) (n = 8); MI Paste (GC, Japan) (n = 8); Paradontax (Sensodyne, Glaxosmithklein, USA) (n = 9); Pronamel (Sensodyne, Glaxosmithklein, USA) (n = 9); Control (n = 9) groups. Samples were carried out five pH cycles along 7 days at 37°C for each group. During pH cycling, blocks were put in a demineralization (6 h) and a remineralization solution (18 h). The treatment consisted of 1 min. interaction of enamel surfaces with agent/deionized slurries (1:3 w/w) on a daily basis. The surface microhardness (SMH) was determined before and after pH cycling with a Digital Micro-Vickers Hardness Tester (Wilson Wolpert; Europe BV, 401 MVD, Netherlands). Mineral changes were determined by using FluoreCam® and recovery values were calculated as SMHR% and FΔ%, respectively.
All groups showed an enhanced remineralization. There was no significant difference in terms of FΔ% (F = 1.223, P = 0.304) and SMHR% (F = 0.709, P = 0.664) between all groups.
The herbals (ginger, honey, and bitter chocolate) examined in this study gave promising results with a high remineralization potential.
在最近的文献中,人们对天然产物的健康益处给予了极大关注。
本研究旨在测量姜-蜜-巧克力混合物的功效,因为之前的文献已经证明了这种混合物具有再矿化作用,并评估这种混合物、姜、天然蜂蜜、苦巧克力单独对初始釉质龋损再矿化的作用。
所有标本均分为八组:姜(土耳其的 Arifoglu®)粉末形式(n = 8);姜-蜜-巧克力(n = 8);天然蜂蜜(土耳其的 Balparmak Plateau Blossom Honey®)(n = 9);苦巧克力(瑞士的 Nestlé®)(n = 8);MI Paste(GC,日本)(n = 8);Paradontax(Sensodyne,Glaxosmithklein,美国)(n = 9);Pronamel(Sensodyne,Glaxosmithklein,美国)(n = 9);对照组(n = 9)。每个组在 37°C 下进行 7 天 5 个 pH 循环。在 pH 循环过程中,将样本在脱矿化(6 h)和再矿化溶液(18 h)中放置。处理方法是每天将牙釉质表面与试剂/去离子浆料(1:3 w/w)接触 1 分钟。用数字显微维氏硬度计(Wilson Wolpert;欧洲 BV,401 MVD,荷兰)在 pH 循环前后测定表面显微硬度(SMH)。用 FluoreCam®测定矿物质变化,并分别计算恢复值作为 SMHR%和 FΔ%。
所有组均表现出增强的再矿化作用。所有组之间的 FΔ%(F = 1.223,P = 0.304)和 SMHR%(F = 0.709,P = 0.664)差异均无统计学意义。
本研究中检查的草药(姜、蜂蜜和苦巧克力)具有很高的再矿化潜力,结果令人鼓舞。