Department of Prosthodontics, Faculty of Dentistry, Erciyes University, Kayseri, Turkey.
Department of Prosthodontics, Faculty of Dentistry, Alanya Alaaddin Keykubat University, Antalya, Turkey.
Niger J Clin Pract. 2021 Sep;24(9):1373-1379. doi: 10.4103/njcp.njcp_666_20.
The purpose of this study was to investigate the fracture resistance, biocompatibility, hardness, and transverse strength of non-precious metal alloy (chromium-cobalt; Cr-Co), titanium (Ti), zirconia (Zr), polymethylmethacrylate (PMMA), and polyetheretherketone (PEEK) when employed as substructure materials according to the implant supported full arch fixed prosthesis treatment concept.
In total, 150 Cr-Co, Ti, Zr, PMMA, and PEEK samples (n = 30 per material) measuring 25 × 2 × 2 mm in size were produced. Of the samples, 50 (n = 10 for each material, all having dimensions of 6 × 3 mm) were subjected to biocompatibility tests. The Vickers hardness test and three-point bending test were performed; fracture resistance measurements were taken and the biocompatibility of the samples was evaluated by the XTT assay.
Vickers hardness was highest for Zr (p < 0.05). PEEK and PMMA had the lowest (and similar) fracture resistance values (p < 0.05). Cell proliferation on the surfaces of the materials was similar between PEEK and Zr (p > 0.05), which were the most biocompatible materials.
Within the limitations of this study, the most favorable materials in terms of biocompatibility were found as PEEK and Zr. When biomechanical properties are evaluated, the most durable materials can be specified as Cr-Co and Zr. Also, further studies are needed to improve material stability.
本研究旨在探讨非贵金属合金（铬-钴；Cr-Co）、钛（Ti）、氧化锆（Zr）、聚甲基丙烯酸甲酯（PMMA）和聚醚醚酮（PEEK）作为种植体支持全弓固定义齿治疗概念的底层材料的抗折力、生物相容性、硬度和抗横向强度。
共制作了 150 个 Cr-Co、Ti、Zr、PMMA 和 PEEK 样本（每种材料 30 个，尺寸均为 25×2×2mm）。其中，50 个样本（每种材料各 10 个，尺寸均为 6×3mm）进行生物相容性测试。进行维氏硬度测试和三点弯曲测试；测量抗折力并通过 XTT 法评估样本的生物相容性。
Zr 的维氏硬度最高（p<0.05）。PEEK 和 PMMA 的抗折力最低（且相似）（p<0.05）。材料表面的细胞增殖在 PEEK 和 Zr 之间相似（p>0.05），这两种材料具有最佳的生物相容性。
在本研究的限制范围内，最具生物相容性的材料为 PEEK 和 Zr。在评估生物力学性能时，最耐用的材料为 Cr-Co 和 Zr。此外，还需要进一步的研究来提高材料的稳定性。
