Teng Tiffany Zhang, Beavogui Abdoul Habib, Diarra Bassirou, Delamou Alexandre, Holl Jane, Maiga Almoustapha Issiaka, Sadio Sarro Yeya Dit, Kone Amadou, Kone Bourahima, Fofana Djeneba Bocar, Dembele Etienne, Sow Mamadou Saliou, Seydi Moussa, Oumar Aboubacar Alassane, Diakité Mahamadou, Diallo Souleymane, Doumbia Seydou, Dao Sounkalo, Murphy Robert L, Maiga Mamoudou
Institute for Global Health, Northwestern University, Chicago, Illinois, USA.
Centre National de Formation et de Recherche en Santé Rurale de Maferinyah, Forécariah, Guinea.
Infect Dis Diagn Treat. 2020;4(2). Epub 2020 Feb 21.
The 2014-2016 Ebola epidemic in Guinea highlighted the need for more extensive evaluation of laboratories diagnostic capacities and preparedness in anticipation of future emerging viral disease outbreaks. We developed a questionnaire to assess the diagnostic capacities and preparedness of the four major medical laboratories in Guinea and Mali that are responsible for the provision of Ebola, Lassa, and Dengue diagnostics. The questionnaire inquired about the current state and need for equipment and reagents and adequacy of equipment and training received. In Guinea, all three diagnostic laboratories have the capacity and are well-prepared to perform Ebola diagnostics, however, only two have the capacity and trained staff to diagnose Lassa and none are currently prepared to diagnose Dengue infection. In Mali, the University Clinical Research Center (UCRC) laboratory, which was in charge of Ebola diagnostics during the last epidemic, currently has the capacity and is prepared to diagnose Ebola, Lassa, and Dengue infections. Combined, Guinea and Mali appear to have complementary capacity and preparedness to diagnose these Category A Priority Pathogens. While, the equipment, reagents and training efforts should be maintained, the gap in Dengue diagnostic capability in Guinea should be addressed with further equipping and training of additional district laboratories to strengthen the public health response for all viral diseases in these high-risk, yet, low-resource settings.
2014 - 2016年几内亚的埃博拉疫情凸显了在预期未来出现病毒性疾病暴发时,需要对实验室诊断能力和准备情况进行更广泛评估。我们设计了一份问卷,以评估几内亚和马里负责提供埃博拉、拉沙热和登革热诊断的四个主要医学实验室的诊断能力和准备情况。问卷询问了设备和试剂的现状与需求,以及所接受设备和培训的充足程度。在几内亚,所有三个诊断实验室都有能力且准备充分可进行埃博拉诊断,然而,只有两个实验室有能力且有经过培训的人员诊断拉沙热,目前没有一个实验室准备好诊断登革热感染。在马里,在上次疫情期间负责埃博拉诊断的大学临床研究中心(UCRC)实验室,目前有能力且准备好诊断埃博拉、拉沙热和登革热感染。综合来看,几内亚和马里在诊断这些甲类优先病原体方面似乎具有互补的能力和准备情况。虽然应维持设备、试剂和培训工作,但几内亚登革热诊断能力的差距应通过进一步为更多地区实验室配备设备和培训来解决,以加强在这些高风险但资源匮乏地区针对所有病毒性疾病的公共卫生应对措施。