Hedner K, Gustafson L, Steen G, Steen B
Department of Community Health Sciences, Lund University, Sweden.
Compr Gerontol A. 1987 Jun;1(2):55-60.
75 patients, aged 69 to 97 (mean 84) years, admitted to a geriatric clinic with symptoms or signs of organic brain failure, were examined with a wide test battery including chemical analyses, electroencephalogram (EEG), regional cerebral blood flow (rCBF) measurement, and psychometric tests. There was a prevalence of 89% organic dementia, 3% treatable dementia, and 8% non-dementia conditions. Thus the prevalence of treatable conditions was rather low (11%). Multi-infarct dementia was more prevalent (52%) than dementia of Alzheimer type (31%). All but one of the non-dementia conditions were due to confusional reaction. In no case was depression, drug intoxication, or deafness the only cause of symptoms. After a follow-up period of 6 months, 33% of the patients had died. An autopsy was performed in 80% of these cases, and the clinical diagnosis was confirmed in all but four cases.
75名年龄在69至97岁（平均84岁）之间、因器质性脑功能衰竭症状或体征而入住老年病诊所的患者，接受了一系列广泛的检查，包括化学分析、脑电图（EEG）、局部脑血流量（rCBF）测量和心理测试。其中，器质性痴呆的患病率为89%，可治疗性痴呆为3%，非痴呆状态为8%。因此，可治疗疾病的患病率相当低（11%）。多发性梗死性痴呆比阿尔茨海默型痴呆更常见（52%比31%）。除1例非痴呆状态外，其余均由意识模糊反应引起。在任何情况下，抑郁、药物中毒或耳聋都不是症状的唯一原因。经过6个月的随访期，33%的患者死亡。其中80%的病例进行了尸检，除4例病例外，其余所有病例的临床诊断均得到证实。
