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鼻腔内给予氟哌啶醇在急性精神病学单元中的疗效和安全性：一项针对轻度至中度激越的精神分裂症患者的初步研究。

Efficacy and safety of intranasal haloperidol in an acute Psychiatry Unit: a pilot study on schizophrenic patients with mild-modedate agitation.

机构信息

Mental Health Service, Parc Taulí University Hospital, Autonomous University of Barcelona, CIBERSAM Translational Neuroscience Unit, Parc Taulí University Hospital, Autonomous University of Barcelona, Sabadell, Barcelona.

Statistics and Evaluation Unit, Parc Taulí Research and Innovation Institute, Autonomous University of Barcelona, Sabadell, Barcelona.

出版信息

Actas Esp Psiquiatr. 2021 Sep;49(5):205-209. Epub 2021 Sep 1.

PMID:34533203
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9335081/
Abstract

To study the efficacy and safety of intranasal administration of 5 mg haloperidol on mild-moderate agitated patients with schizophrenia or schizoaffective disorder in an acute psychiatry unit setting.

摘要

研究在急性精神病病房环境中，经鼻腔给予 5 毫克氟哌啶醇对轻中度激越精神分裂症或分裂情感障碍患者的疗效和安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02e6/9335081/14c815b9d1d2/ActEsp-49-5-205-209-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02e6/9335081/14c815b9d1d2/ActEsp-49-5-205-209-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02e6/9335081/14c815b9d1d2/ActEsp-49-5-205-209-F1.jpg

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本文引用的文献

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Intravenous haloperidol: A systematic review of side effects and recommendations for clinical use.静脉注射氟哌啶醇：副作用的系统评价及临床应用建议。
Gen Hosp Psychiatry. 2020 Nov-Dec;67:42-50. doi: 10.1016/j.genhosppsych.2020.08.008. Epub 2020 Aug 22.
2
Protocol for the management of psychiatric patients with psychomotor agitation.伴有精神运动性激越的精神病患者管理方案
BMC Psychiatry. 2017 Sep 8;17(1):328. doi: 10.1186/s12888-017-1490-0.
3
Review of Intranasally Administered Medications for Use in the Emergency Department.
急诊科使用的经鼻给药药物综述。
J Emerg Med. 2017 Jul;53(1):38-48. doi: 10.1016/j.jemermed.2017.01.020. Epub 2017 Mar 1.
4
Issues in the management of acute agitation: how much current guidelines consider safety?急性激越管理中的问题：现行指南在多大程度上考虑了安全性？
Front Psychiatry. 2013 May 7;4:26. doi: 10.3389/fpsyt.2013.00026. eCollection 2013.
5
Validation of the Excited Component of the Positive and Negative Syndrome Scale (PANSS-EC) in a naturalistic sample of 278 patients with acute psychosis and agitation in a psychiatric emergency room.在精神科急诊室 278 例急性精神病和激越患者的自然样本中验证阳性和阴性综合征量表兴奋成分 (PANSS-EC)。
Health Qual Life Outcomes. 2011 Mar 29;9:18. doi: 10.1186/1477-7525-9-18.
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The clinical global impressions scale: applying a research tool in clinical practice.临床总体印象量表：在临床实践中应用一种研究工具。
Psychiatry (Edgmont). 2007 Jul;4(7):28-37.
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