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儿科微创手术中的生活质量:腹腔镜与开腹阑尾切除术的成本效用分析。

Quality of Life in Pediatric Minimally Invasive Surgery: Cost-Utility Analysis of Laparoscopic Versus Open Appendectomy.

机构信息

Pediatric Surgery Department, Mútua de Terrassa University Hospital, Terrassa, Barcelona, Spain.

Instituto de Validación de la Eficiencia Clínica (IVEC), Cátedra de Medicina Basada en la Eficiencia, Fundación de Investigación HM Hospitales, Madrid. Spain.

出版信息

J Laparoendosc Adv Surg Tech A. 2022 Feb;32(2):219-225. doi: 10.1089/lap.2021.0495. Epub 2021 Sep 17.

Abstract

Economic evaluation in health care is becoming increasingly important. Laparoscopic appendectomy (LAp) is one of the most frequent minimally invasive procedures in the pediatric population. The increased costs of this approach in any indication could be justified by proving its cost-utility in terms of health-related quality of life (HRQoL). We aim to perform a cost-utility analysis between open and LAp (open appendectomy [OAp] and LAp). We included the data of children operated for acute noncomplicated appendicitis, who agreed to answer a validated quality of life (QoL) questionnaire. Costs were calculated for each patient. We established a threshold for cost-effectiveness (λ) of 20,000 to 30,000€ per quality adjusted life year (QALY) according to previous research. A total of 53 patients were included. Overall mean costs in the OAp were 758.98€ and in the LAp 1525.50€. The incremental cost-effectiveness ratio was 18,000€/QALY, under the threshold of cost-effectiveness, therefore favoring the laparoscopic approach as it improves HRQoL despite the costs. Economic evaluation studies in Pediatric Surgery are scarce and rarely measure outcomes in terms of QoL. This information is important in the decision-making process for institutions and health-care professionals. Our results encourage the use of laparoscopy in pediatric appendectomy to improve HRQoL in our patients.

摘要

卫生保健中的经济评价变得越来越重要。腹腔镜阑尾切除术(LAp)是儿科人群中最常见的微创程序之一。在任何适应症下,这种方法的成本增加,如果能证明其在健康相关生活质量(HRQoL)方面的成本效益,就可以得到证明。我们旨在对开腹手术(OAp)和 LAp 之间进行成本-效用分析。我们纳入了接受急性非复杂性阑尾炎手术的儿童的数据,这些儿童同意回答经过验证的生活质量(QoL)问卷。为每个患者计算了成本。根据先前的研究,我们为成本效益设定了一个阈值(λ)为 20,000 至 30,000 欧元/QALY。共纳入 53 例患者。OAp 的总体平均成本为 758.98 欧元,LAp 的总体平均成本为 1525.50 欧元。增量成本效益比为 18,000 欧元/QALY,低于成本效益阈值,因此支持腹腔镜方法,因为它可以提高 HRQoL,尽管成本较高。儿科外科的经济评价研究很少,很少以 QoL 来衡量结果。这些信息对机构和医疗保健专业人员的决策过程很重要。我们的研究结果鼓励在小儿阑尾切除术中使用腹腔镜,以提高我们患者的 HRQoL。

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