Department of Psychiatry, Grant Medical College and Sir JJ Group Of Hospitals, Mumbai, Maharashtra, India.
Consultant Psychiatrist, BRAMHA Hospital & ASSSAN Hospital, Nagpur, Maharashtra, India.
Psychiatry Res. 2021 Nov;305:114203. doi: 10.1016/j.psychres.2021.114203. Epub 2021 Sep 5.
A longer duration of untreated psychosis (DUP) may adversely affect the course and impact of the illness. Little is known about predictors of duration of untreated psychosis in lower socioeconomic strata (SES) in urban India. We examined variables associated with DUP in 60 urban lower SES patients diagnosed with first-episode, untreated psychosis. Instruments used included the Positive and Negative Syndrome Scale (PANSS), the Global Assessment of Functioning (GAF), the UCLA Social Attainment Scale (SAS), and the Stigma Subscale from the Family Interview Schedule. The mean age of the sample was 30.5 years. The sample was 50% male. Most patients (90%) were living in a nuclear family. The median DUP was 120 days. DUP was <6 months in 31.7% of the sample and >2 years in 23.3%. A third of the sample had been taken to faith healers before being brought into medical care. DUP was not significantly associated with age, sex, religion, education, family history of mental illness, marital status, employment status, income, substance use, PANSS subscale and total scale scores, and GAF scores. Presence of an antecedent stressor, acute onset of psychosis, presence of medical co-morbidities, lower stigma scores, and higher SAS scores were significantly associated with shorter DUP.
未治疗精神病期（DUP）较长可能会对疾病的病程和影响产生不利影响。在印度城市中，社会经济地位较低的人群中，DUP 的预测因素知之甚少。我们研究了 60 名首次确诊未经治疗的精神病的城市中社会经济地位较低的患者与 DUP 相关的变量。使用的工具包括阳性和阴性症状量表（PANSS）、总体功能评估（GAF）、加州大学洛杉矶分校社会成就量表（SAS）和家庭访谈时间表的耻辱感量表。样本的平均年龄为 30.5 岁。样本中 50%为男性。大多数患者（90%）居住在核心家庭中。DUP 的中位数为 120 天。31.7%的样本的 DUP<6 个月，23.3%的样本的 DUP>2 年。三分之一的样本在接受医疗护理之前曾被信仰治疗者治疗过。DUP 与年龄、性别、宗教、教育、精神疾病家族史、婚姻状况、就业状况、收入、物质使用、PANSS 分量表和总量表评分以及 GAF 评分均无显著相关性。有前期压力源、精神病急性发作、合并躯体疾病、耻辱感量表评分较低和 SAS 量表评分较高与 DUP 较短显著相关。
