Thomas A
Department of Statistics and Computational Mathematics, Brownlow Hill.
IMA J Math Appl Med Biol. 1986;3(3):157-66. doi: 10.1093/imammb/3.3.157.
Approximation by factorization of R functions is considered as a way of making the peeling method for calculation of probability functions more efficient and applicable to larger and more complex pedigrees. We show that, in some situations, the method is not approximate but a simplified way of calculating the true probability functions. The entropy function is used for a measure of the quality of factorization. The method is illustrated by an analysis of the origin of the B allele in the ABO blood type system on Tristan da Cunha.
通过R函数的因式分解进行近似被认为是一种使计算概率函数的剥离方法更高效且适用于更大、更复杂家系的方式。我们表明,在某些情况下,该方法并非近似方法,而是一种计算真实概率函数的简化方式。熵函数用于衡量因式分解的质量。通过对特里斯坦 - 达库尼亚群岛ABO血型系统中B等位基因起源的分析来说明该方法。