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微生物代谢产物:增强癌症治疗效果的新型治疗工具。

Microbial metabolites: novel therapeutic tools for boosting cancer therapies.

作者信息

Luu Maik, Visekruna Alexander

机构信息

Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.

Institute for Medical Microbiology and Hygiene, Philipps-University Marburg, Marburg, Germany.

出版信息

Trends Cell Biol. 2021 Nov;31(11):873-875. doi: 10.1016/j.tcb.2021.08.005. Epub 2021 Sep 17.

DOI:10.1016/j.tcb.2021.08.005
PMID:34538658
Abstract

The microbiome is a hidden treasure trove comprising various microorganisms that produce a wide range of bioactive molecules. Recent studies provide evidence for the potential impact of microbiota on cancer therapies. Here, we summarize how the molecular interaction of two groups of microbial metabolites with T cells improves immunotherapy for cancer.

摘要

微生物组是一个隐藏的宝库,由产生多种生物活性分子的各种微生物组成。最近的研究为微生物群对癌症治疗的潜在影响提供了证据。在这里,我们总结了两组微生物代谢产物与T细胞的分子相互作用如何改善癌症免疫治疗。

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