Chen Wen, Chen Baohua, Wang Fengxiang, Wu Qingsong, Liu Wenying, Wei Hong, Li Changke
Department of Anesthesiology, Yuebei People's Hospital Affiliated to Shantou University Medical College, Shaoguan, Guangdong 512026, China.
Department of General Surgery, The 908th Hospital of Chinese People's Liberation Army Joint Logistic Support Force, Yingtan, Jiangxi 335001, China.
Evid Based Complement Alternat Med. 2021 Sep 7;2021:1426753. doi: 10.1155/2021/1426753. eCollection 2021.
Partial hepatectomy under general anesthesia is prone to hemodynamic alterations, and stress reactions are the main contributing factors to postoperative cognitive function in elderly partial hepatectomy patients. Postoperative cognitive dysfunction increases the incidence of postoperative complications and long-term morbidity and mortality in elderly patients. With the increasing trend of aging population and the gradual increase of elderly people undergoing surgical treatment, it is especially important to study the corresponding prevention and treatment measures. In this study, a total of 90 patients with primary liver cancer who received hepatectomy in our hospital from July 2020 to July 2021 were included as the research subject. The changes in hemorheology, stress-related indexes, cognitive function, postoperative pain, and gastrointestinal function were compared between the two groups The results showed that SGB combined with general anesthesia can effectively reduce hemodynamic fluctuations in elderly partial hepatectomy patients, alleviate surgical stress, promote postoperative recovery of cognitive function and gastrointestinal function with high safety, and is worthy of clinical promotion.
全身麻醉下的肝部分切除术容易出现血流动力学改变，而应激反应是老年肝部分切除术患者术后认知功能的主要影响因素。术后认知功能障碍增加了老年患者术后并发症的发生率以及长期发病率和死亡率。随着人口老龄化趋势的加剧以及接受手术治疗的老年人逐渐增多，研究相应的防治措施尤为重要。本研究纳入了2020年7月至2021年7月在我院接受肝切除术的90例原发性肝癌患者作为研究对象。比较了两组患者血液流变学、应激相关指标、认知功能、术后疼痛及胃肠功能的变化。结果表明，星状神经节阻滞联合全身麻醉可有效降低老年肝部分切除术患者的血流动力学波动，减轻手术应激，促进术后认知功能和胃肠功能恢复，安全性高，值得临床推广。
