Department of Anesthesiology, People's Hospital of Deyang City, Deyang, Sichuan 618000, China.
People's Hospital of Deyang City, No. 173 Taishan Road, Deyang, Sichuan Province, China.
Comput Intell Neurosci. 2022 Jul 14;2022:2056969. doi: 10.1155/2022/2056969. eCollection 2022.
The aim of the study was to study the effects of the ultrasound-guided stellate ganglion block on hemodynamics, stressful response, and postoperative gastrointestinal functions in patients with colorectal cancer.
A total of 100 patients with colorectal cancer hospitalized from January 2021 to December 2021 were selected. After anesthesia induction, the right stellate ganglion block was performed under ultrasound guidance in the research group and the general anesthesia was performed in the control group. The heart rate (HR), mean arterial pressure (MAP), epinephrine, cortisol, self-rating anxiety scale (SAS), Ramsay sedation score (RSS), postoperative bowel sound recovery time, anal exhaust time, and the incidence of gastrointestinal adverse reactions 24 hours after operation were studied pre-and post-24-hour anesthesia induction.
Following 24-hour operation, the HR and MAP values were largely reduced ( < 0.05). Following 24-hour operation, epinephrine and cortisol became obviously higher ( < 0.05). After 24-hour operation, the levels of epinephrine and cortisol in the research group were greatly lower. The score of the SAS in the study cohort was less than that of the controls ( < 0.05). The RSS of the research group was obviously increased ( < 0.05). The recovery time of intestinal sound and the anal exhaust time of the study cohort became remarkably shorter ( < 0.05). The incidence of gastrointestinal adverse reactions 24 hours after operation of the study cohort was much less common ( < 0.05).
The ultrasound-guided stellate ganglion block can reduce the fluctuation of blood circulation during radical resection of colorectal cancer, reduce postoperative gastrointestinal dysfunction and stress reaction, relieve patients' anxiety, and contribute to the recovery of gastrointestinal function.
本研究旨在探讨超声引导下星状神经节阻滞对结直肠癌患者血流动力学、应激反应和术后胃肠功能的影响。
选取 2021 年 1 月至 12 月收治的 100 例结直肠癌患者,麻醉诱导后,研究组在超声引导下行右侧星状神经节阻滞,对照组行全身麻醉。研究麻醉诱导前及术后 24 小时的心率(HR)、平均动脉压(MAP)、肾上腺素、皮质醇、焦虑自评量表(SAS)、Ramsay 镇静评分(RSS)、术后肠鸣音恢复时间、肛门排气时间及术后 24 小时胃肠道不良反应发生率。
术后 24 小时,HR 和 MAP 值明显降低( < 0.05);术后 24 小时,肾上腺素和皮质醇明显升高( < 0.05);术后 24 小时,研究组肾上腺素和皮质醇水平明显降低;研究组 SAS 评分低于对照组( < 0.05);研究组 RSS 明显升高( < 0.05);研究组肠鸣音恢复时间和肛门排气时间明显缩短( < 0.05);术后 24 小时研究组胃肠道不良反应发生率明显较低( < 0.05)。
超声引导下星状神经节阻滞可减少结直肠癌根治术患者循环波动,降低术后胃肠功能障碍和应激反应,缓解患者焦虑,有利于胃肠功能恢复。