Ejaz Ayesha, Junejo Abdul Manan, Ali Muhammad, Ashfaq Ahsan, Hafeez Abdul Rauf, Khan Sadaqat Ali
Nephrology, Jinnah Postgraduate Medical Centre, Karachi, PAK.
Nephrology, Fazaia Ruth Pfau Medical College, Karachi, PAK.
Cureus. 2021 Aug 8;13(8):e17006. doi: 10.7759/cureus.17006. eCollection 2021 Aug.
Background Dialysis-associated morbidity and mortality among end-stage renal disease (ESRD) patients has been increasing, despite the advancement in pharmacological treatment and dialysis technology. The aim of this study was to determine the outcomes of dialysis among ESRD patients presenting at the nephrology department of Jinnah Postgraduate Medical Centre (JPMC). Methodology This cross-sectional study was conducted during the year 2015-2016, including 105 ESRD patients. Data were collected through a structured questionnaire inquiring about patient's demographics and hemodialysis details. The outcomes in terms of survival and death within one month of dialysis were also recorded. The statistical analysis was carried out using SPSS version 21.0 (IBM Corp, Armonk, NY). Results Gender distribution showed that most of the study patients were males (58.1%). The mean duration of ESRD was 7.65 ± 3.69 months while the mean duration of hemodialysis was 36.5 ± 5.65 hours. Among the comorbid conditions, hypertension (69.5%) and diabetes (64.8%) were the most prevalent, followed by renal stones, chronic pyelonephritis, and chronic nephritis. The outcomes indicated mortality among 16.2% of patients; all deceased ESRD patients had diabetes (p < 0.05). Moreover, the duration of hemodialysis was significantly associated with the outcomes of dialysis (p < 0.05). Conclusion In conclusion, a considerable mortality rate was observed among ESRD patients undergoing hemodialysis. Moreover, patient survival was better with the increased duration of dialysis.
背景 尽管药物治疗和透析技术有所进步，但终末期肾病（ESRD）患者的透析相关发病率和死亡率仍在上升。本研究的目的是确定在真纳研究生医学中心（JPMC）肾病科就诊的ESRD患者的透析结果。 方法 本横断面研究于2015年至2016年期间进行，纳入105例ESRD患者。通过结构化问卷收集数据，询问患者的人口统计学信息和血液透析细节。还记录了透析后一个月内的生存和死亡结果。使用SPSS 21.0版（IBM公司，纽约州阿蒙克）进行统计分析。 结果 性别分布显示，大多数研究患者为男性（58.1%）。ESRD的平均病程为7.65±3.69个月，而血液透析的平均时长为36.5±5.65小时。在合并症中，高血压（69.5%）和糖尿病（64.8%）最为常见，其次是肾结石、慢性肾盂肾炎和慢性肾炎。结果表明16.2%的患者死亡；所有死亡的ESRD患者均患有糖尿病（p<0.05）。此外，血液透析时长与透析结果显著相关（p<0.05）。 结论 总之，接受血液透析的ESRD患者死亡率较高。此外，透析时长增加患者生存率更高。
