Saha Arpita, Saha Kaushik, Sarkar Nilanjan, Geelani Ishfaq A
Pathology, Manipal Tata Medical College, Manipal Academy of Higher Education, Jamshedpur, IND.
Pathology, Tata Main Hospital, Jamshedpur, IND.
Cureus. 2021 Aug 17;13(8):e17265. doi: 10.7759/cureus.17265. eCollection 2021 Aug.
Paraganglioma of the urinary bladder is a rare neoplasm. It may be functional, secreting catecholamines, or nonfunctional. Clinically and histopathologically, it has the potential to be misdiagnosed as a more common urothelial carcinoma, especially in nonfunctional cases. A high index of suspicion on the part of pathologist can help in identification of characteristic histopathologic feature which coupled with immunohistochemistry can help in establishing the correct diagnosis. We present a case of paraganglioma in a 78-year-old male patient presenting with haematuria. Clinical provisional diagnosis rendered based on cystoscopic findings and radiology was urothelial carcinoma; however, was confirmed to be a case of paraganglioma of bladder on histopathological and immunohistochemical evaluation. A long follow-up is warranted. Herein, we also briefly review the relevant literature.
膀胱副神经节瘤是一种罕见的肿瘤。它可能具有功能，分泌儿茶酚胺，也可能无功能。在临床和组织病理学上，它有可能被误诊为更常见的尿路上皮癌，尤其是在无功能的病例中。病理学家保持高度的怀疑指数有助于识别特征性的组织病理学特征，结合免疫组织化学有助于做出正确的诊断。我们报告一例78岁男性血尿患者的膀胱副神经节瘤病例。基于膀胱镜检查结果和影像学做出的临床初步诊断为尿路上皮癌；然而，经组织病理学和免疫组织化学评估证实为膀胱副神经节瘤病例。需要进行长期随访。在此，我们还简要回顾了相关文献。
