Selk-Ghaffari Maryam, Shab-Bidar Sakineh, Halabchi Farzin
Sports Medicine Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Iran J Public Health. 2021 Jun;50(6):1120-1134. doi: 10.18502/ijph.v50i6.6411.
Due to widespread abuse of anabolic-androgenic steroids among professional athletes and amateur sportsmen and their health-related problems, determining the prevalence and the pattern of anabolicandrogenic steroid misuse at the national level seems to be vital for designing efficient preventive and educational measures.
This systematic review and meta-analysis was conducted via comprehensive searches of the electronic databases including PubMed, MedLine, Scopus, Google Scholar and National Persian Databases including SID, Magiran, IranDoc (between 1980 and Dec 2019 in English and Persian languages) and also from citations in the selected papers. Overall, 39 articles met the criteria and were included in qualitative and quantitative synthesis.
The overall prevalence rate of anabolic-androgenic steroid misuse in the Iranian athletic population was 36.2% (95% confidence interval (CI), 29-43) with significant heterogeneity between studies (I=99.0%, <0.001). Prevalence rate of anabolic-androgenic steroid misuse among elite, male and younger athletes was higher (<0.05). Moreover, prevalence rate of anabolic-androgenic steroid misuse among body-building athletes (36.3%) was higher compared to other athletes (30.9%), (<0.001).
Due to the higher prevalence of anabolic-androgenic steroids misuse in Iran compared to global statistics and the potential for serious adverse effects, preventive strategies and policies should be regarded as a real concern for public health.
由于合成代谢雄激素类固醇在职业运动员和业余运动员中被广泛滥用及其引发的健康相关问题,在国家层面确定合成代谢雄激素类固醇滥用的流行率和模式对于设计有效的预防和教育措施似乎至关重要。
本系统评价和荟萃分析通过全面检索电子数据库进行,包括PubMed、MedLine、Scopus、谷歌学术以及国家波斯语数据库,如SID、Magiran、IranDoc(检索时间为1980年至2019年12月,语言为英语和波斯语),还检索了所选论文中的参考文献。总体而言,39篇文章符合标准并纳入定性和定量综合分析。
伊朗运动员群体中合成代谢雄激素类固醇滥用的总体流行率为36.2%(95%置信区间[CI],29 - 43),各研究间存在显著异质性(I = 99.0%,P < 0.001)。精英运动员、男性运动员和年轻运动员中合成代谢雄激素类固醇滥用的流行率较高(P < 0.05)。此外,健美运动员中合成代谢雄激素类固醇滥用的流行率(36.3%)高于其他运动员(30.9%)(P < 0.001)。
由于伊朗合成代谢雄激素类固醇滥用的流行率高于全球统计数据,且存在严重不良反应的可能性,预防策略和政策应被视为公共卫生的真正关注点。