Suppr超能文献

老年腹股沟疝修补术中围手术期继续抗血栓治疗的安全性

Safety of Inguinal Hernia Repair in the Elderly with Perioperative Continuation of Antithrombotic Therapy.

作者信息

Hada Gonish, Zhang Sen, Song Yinghan, Jaiswar Mukesh, Xie Yanyan, Jian Fushan, Lei Wenzhang

机构信息

Department of Gastrointestinal Surgery, Hernia Center, West China Hospital, Sichuan University, Chengdu, China.

Department of Day Care Surgery, West China Hospital, Sichuan University, Chengdu, China.

出版信息

Visc Med. 2021 Aug;37(4):315-322. doi: 10.1159/000509895. Epub 2020 Nov 6.

Abstract

INTRODUCTION

This study aimed to evaluate the safety of an inguinal hernia repair (IHR) under local anesthesia (LA) in the elderly with a perioperative continuation of antithrombotic therapy (AT).

METHODS

A total of 120 patients undergoing elective primary IHR between August 2018 and August 2019 at the West China Hospital of China were prospectively studied, among which 60 patients also had coexisting cardiovascular diseases and had a continuation of AT perioperatively (antithrombotic group); the other 60 patients were not on any prior AT (control group). The primary endpoints were intra- and postoperative hemorrhagic complications, the required interventions for complications based on the Clavien-Dindo classification, and postoperative thromboembolic complications. The secondary endpoints were nonhemorrhagic complications, intraoperative duration, and postoperative length of stay (LOS).

RESULTS

None of the patients in both groups had significant intraoperative bleeding >10 mL, and there were no significant differences between the 2 groups in terms of the postoperative hemorrhagic complications: bruising (2 vs. 0%, = 1.000), serosanguinous soakage (7 vs. 3%, = 0.679), and no hematoma was observed. Interventions required for encountered complications based on the Clavien-Dindo classification grade I (7 vs. 5%, = 1.000) were assessed. There were no episodes of postoperative thromboembolic complications within 60 days in both groups. There were also no significant differences between the 2 groups in terms of nonhemorrhagic complications, intraoperative duration, and postoperative LOS ( > 0.05 in all).

CONCLUSIONS

The perioperative continuation of AT did not increase the risk of intra- and postoperative hemorrhagic complications following IHR in the elderly. Thus, IHR under LA seems to be safe and feasible in this setting.

摘要

引言

本研究旨在评估在局部麻醉下对老年患者进行腹股沟疝修补术(IHR)并在围手术期继续进行抗血栓治疗(AT)的安全性。

方法

对2018年8月至2019年8月在中国华西医院接受择期原发性IHR的120例患者进行前瞻性研究,其中60例患者同时患有心血管疾病并在围手术期继续进行AT(抗血栓组);另外60例患者术前未进行任何AT(对照组)。主要终点是术中和术后出血并发症、根据Clavien-Dindo分类法对并发症所需的干预措施以及术后血栓栓塞并发症。次要终点是非出血性并发症、术中持续时间和术后住院时间(LOS)。

结果

两组患者术中均无明显出血>10 mL,两组术后出血并发症方面无显著差异:瘀斑(2% vs. 0%,P = 1.000)、血清渗出(7% vs. 3%,P = 0.679),且未观察到血肿。根据Clavien-Dindo分类法评估I级并发症所需的干预措施(7% vs. 5%,P = 1.000)。两组在60天内均无术后血栓栓塞并发症发生。两组在非出血性并发症、术中持续时间和术后LOS方面也无显著差异(均P>0.05)。

结论

围手术期继续进行AT不会增加老年患者IHR术后术中和术后出血并发症的风险。因此,在这种情况下,局部麻醉下的IHR似乎是安全可行的。

相似文献

本文引用的文献

8
Withdrawal of Antithrombotic Agents and the Risk of Stroke.抗血栓药物的停用与中风风险
J Stroke Cerebrovasc Dis. 2016 Apr;25(4):902-6. doi: 10.1016/j.jstrokecerebrovasdis.2016.01.006. Epub 2016 Jan 28.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验