• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

踝关节镜检查及骨髓刺激治疗距骨骨软骨损伤后早期负重的影响

Impact of Early Weightbearing After Ankle Arthroscopy and Bone Marrow Stimulation for Osteochondral Lesions of the Talus.

作者信息

Danilkowicz Richard M, Grimm Nathan L, Zhang Gloria X, Lefebvre Thomas A, Lau Brian, Adams Samuel B, Amendola Annunziato

机构信息

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina, USA.

Idaho Sports Medicine Institute, Boise, Idaho, USA.

出版信息

Orthop J Sports Med. 2021 Sep 13;9(9):23259671211029883. doi: 10.1177/23259671211029883. eCollection 2021 Sep.

DOI:10.1177/23259671211029883
PMID:34541014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8442498/
Abstract

BACKGROUND

Osteochondral lesion of the talus (OLT) may be caused by osteochondritis dissecans, osteochondral fractures, avascular necrosis, or focal arthritic changes. For certain focal cartilage defects, bone marrow stimulation (BMS) has been a widely used technique to restore a fibrocartilage substitute overlying the defect. There are various postoperative weightbearing protocols for this procedure, with no single gold standard method.

PURPOSE

To retrospectively review the outcomes of patients undergoing ankle arthroscopy with concomitant BMS to determine outcomes based on postoperative weightbearing status.

STUDY DESIGN

Cohort study; Level of evidence, 3.

METHODS

We retrospectively reviewed the records of patients who underwent ankle arthroscopy with BMS for OLTs between 2015 and 2018. Patients were placed into 2 cohorts based on postoperative immobilization status: the nonweightbearing (NWB) group and the weightbearing-as-tolerated (WBAT) group. Patient characteristics obtained included age, sex, comorbidities, and etiology of talar pathology. Outcomes included the pain visual analog scale (VAS), range of motion (ROM), complications, time to first weightbearing, and the method and length of immobilization. Patients who were lost to follow-up before 30 days were excluded. The chi-square test was used to compare categorical variables between cohorts, and the test was used for continuous variables.

RESULTS

A total of 69 patients met the inclusion criteria for this study, 18 in the WBAT group and 51 in the NWB group. The mean lesion size was 9.48 × 9.21 mm (range, 3-15 mm × 2-20 mm) for the NWB group and 9.36 × 9.72 mm (range, 5-14 mm × 6-20 mm) for the WBAT group ( > .05). The VAS scores improved from 4.40 to 0.67 for the WBAT group and from 6.33 to 2.55 for the NWB group, with the difference in final values reaching statistical significance ( = .0002). Postoperative ROM was not significantly different between the groups. There were 4 repeat operations within the NWB cohort.

CONCLUSION

The surgical management of OLTs can be challenging, and the postoperative weightbearing protocol can be an extra obstacle for the patient to navigate. We found no difference in pain, ROM, or complications when allowing immediate, full WBAT.

摘要

背景

距骨骨软骨损伤(OLT)可能由剥脱性骨软骨炎、骨软骨骨折、缺血性坏死或局灶性关节炎改变引起。对于某些局灶性软骨缺损,骨髓刺激(BMS)一直是一种广泛应用的技术,用于在缺损上方恢复纤维软骨替代物。该手术有多种术后负重方案,没有单一的金标准方法。

目的

回顾性分析接受踝关节镜检查并同时进行BMS的患者的预后,以根据术后负重状态确定预后情况。

研究设计

队列研究;证据等级为3级。

方法

我们回顾性分析了2015年至2018年间因OLT接受踝关节镜检查并进行BMS的患者的记录。根据术后固定状态将患者分为2个队列:非负重(NWB)组和可耐受负重(WBAT)组。获取的患者特征包括年龄、性别、合并症和距骨病变的病因。预后指标包括疼痛视觉模拟量表(VAS)、活动范围(ROM)、并发症、首次负重时间以及固定方法和时间。排除在30天前失访的患者。采用卡方检验比较队列之间的分类变量,采用t检验比较连续变量。

结果

共有69例患者符合本研究的纳入标准,其中WBAT组18例,NWB组51例。NWB组平均损伤大小为9.48×9.21mm(范围3 - 15mm×2 - 20mm),WBAT组为9.36×9.72mm(范围5 - 14mm×6 - 20mm)(P > 0.05)。WBAT组VAS评分从4.40改善至0.67,NWB组从6.33改善至2.55,最终值差异具有统计学意义(P = 0.0002)。两组术后ROM无显著差异。NWB队列中有4例再次手术。

结论

OLT的手术治疗具有挑战性,术后负重方案可能成为患者需要应对的额外障碍。我们发现允许立即完全WBAT时,在疼痛、ROM或并发症方面没有差异。

相似文献

1
Impact of Early Weightbearing After Ankle Arthroscopy and Bone Marrow Stimulation for Osteochondral Lesions of the Talus.踝关节镜检查及骨髓刺激治疗距骨骨软骨损伤后早期负重的影响
Orthop J Sports Med. 2021 Sep 13;9(9):23259671211029883. doi: 10.1177/23259671211029883. eCollection 2021 Sep.
2
Postoperative Weightbearing Protocols After Arthroscopic Surgery for Femoroacetabular Impingement Does Not Affect Patient Outcome: A Comparative Study With Minimum 2-Year Follow-up.关节镜下股骨髋臼撞击症术后负重方案并不影响患者预后:一项至少 2 年随访的对照研究。
Arthroscopy. 2020 Jan;36(1):159-164. doi: 10.1016/j.arthro.2019.08.012.
3
Comparison of early versus delayed weightbearing outcomes after microfracture for small to midsized osteochondral lesions of the talus.微骨折治疗距骨小至中型骨软骨病变后早期与延迟负重的疗效比较。
Am J Sports Med. 2012 Sep;40(9):2023-8. doi: 10.1177/0363546512455316. Epub 2012 Aug 9.
4
Immediate Unrestricted Postoperative Weightbearing and Mobilization after Bone Marrow Stimulation of Large Osteochondral Lesions of the Talus.距骨大骨软骨损伤骨髓刺激术后立即无限制负重及活动
Cartilage. 2017 Jan;8(1):73-79. doi: 10.1177/1947603516657639. Epub 2016 Jul 11.
5
Immediate Unprotected Weightbearing vs 2 Weeks Nonweightbearing After Open Reduction Internal Fixation of Ankle Fractures.踝关节骨折切开复位内固定术后立即无保护负重与2周非负重的比较
Foot Ankle Int. 2024 Feb;45(2):103-114. doi: 10.1177/10711007231217675. Epub 2023 Dec 29.
6
Arthroscopic Treatment of Osteochondral Lesions of the Talus in a Pediatric Population: A Minimum 2-Year Follow-up.关节镜治疗儿童距骨骨软骨病变:至少 2 年随访。
Am J Sports Med. 2020 Jul;48(8):1989-1998. doi: 10.1177/0363546520924800. Epub 2020 Jun 8.
7
Clinical Outcomes of Osteochondral Fragment Fixation Versus Microfracture Even for Small Osteochondral Lesions of the Talus.距骨小骨软骨病变行骨软骨碎块固定术与微骨折术的临床疗效比较。
Am J Sports Med. 2022 Sep;50(11):3019-3027. doi: 10.1177/03635465221109596. Epub 2022 Jul 28.
8
Clinical outcomes of mesenchymal stem cell injection with arthroscopic treatment in older patients with osteochondral lesions of the talus.关节镜下注射间充质干细胞治疗老年距骨骨软骨病变的临床疗效。
Am J Sports Med. 2013 May;41(5):1090-9. doi: 10.1177/0363546513479018. Epub 2013 Mar 4.
9
Osteochondral Autologous Transplantation Is Superior to Repeat Arthroscopy for the Treatment of Osteochondral Lesions of the Talus After Failed Primary Arthroscopic Treatment.自体骨软骨移植术在初次关节镜治疗失败后治疗距骨骨软骨损伤方面优于重复关节镜检查。
Am J Sports Med. 2014 Aug;42(8):1896-903. doi: 10.1177/0363546514535186. Epub 2014 Jun 6.
10
Comparison of Osteochondral Autografts and Allografts for Treatment of Recurrent or Large Talar Osteochondral Lesions.自体骨软骨移植与异体骨软骨移植治疗复发性或大型距骨骨软骨损伤的比较
Foot Ankle Int. 2016 Jan;37(1):40-50. doi: 10.1177/1071100715603191. Epub 2015 Sep 2.

引用本文的文献

1
Results of arthroscopic microfracture treatment for traumatic and non-traumatic osteochondral lesions of the talus: a retrospective cohort study.距骨创伤性和非创伤性骨软骨损伤的关节镜下微骨折治疗结果:一项回顾性队列研究
BMC Musculoskelet Disord. 2025 Jul 25;26(1):709. doi: 10.1186/s12891-025-08949-6.
2
Immediate Postoperative Weightbearing Following Arthroscopic Bone Marrow Stimulation for Talar Osteochondral Lesions: A Matched Cohort Study.关节镜下骨髓刺激治疗距骨骨软骨损伤后的即刻术后负重:一项配对队列研究
Foot Ankle Int. 2025 Jul 10;46(9):10711007251348196. doi: 10.1177/10711007251348196.
3
Recent Advances in the Clinical Treatment of Osteochondral Lesions of the Talus (2021-2023): A Narrative Review.

本文引用的文献

1
Early vs Delayed Weightbearing After Microfracture of Osteochondral Lesions of the Talus: A Prospective Randomized Trial.距骨骨软骨损伤微骨折术后早期负重与延迟负重的前瞻性随机试验
Foot Ankle Orthop. 2019 May 6;4(2):2473011419838832. doi: 10.1177/2473011419838832. eCollection 2019 Apr.
2
Are Weightbearing Restrictions Required After Microfracture for Isolated Chondral Lesions of the Knee? A Review of the Basic Science and Clinical Literature.微骨折治疗膝关节孤立性软骨病变后是否需要负重限制?基础科学和临床文献复习。
Sports Health. 2021 Mar;13(2):111-115. doi: 10.1177/1941738120938662. Epub 2020 Jul 28.
3
距骨骨软骨损伤的临床治疗新进展(2021 - 2023):一项叙述性综述
Orthop Surg. 2025 Jul;17(7):1924-1935. doi: 10.1111/os.70066. Epub 2025 May 15.
4
Functional and radiographic outcomes of talar osteochondral lesions repaired with a combination of autologous bone graft, cell-free hyaluronic acid-based scaffold, bone marrow aspirate concentrate (BMAC) and fibrin glue.采用自体骨移植、无细胞透明质酸基支架、骨髓抽吸浓缩物(BMAC)和纤维蛋白胶联合修复距骨骨软骨损伤的功能和影像学结果。
Int Orthop. 2025 Apr 23. doi: 10.1007/s00264-025-06542-z.
5
Patient characteristics, postoperative protocols, and surgical outcomes in Haglund's resection: a single-institution retrospective cohort study.Haglund切除术的患者特征、术后方案及手术结果:一项单机构回顾性队列研究
Arch Orthop Trauma Surg. 2025 Apr 12;145(1):241. doi: 10.1007/s00402-025-05860-6.
6
Weightbearing Protocols and Outcomes in Open Surgical Management of Haglund Syndrome: A Large Retrospective Analysis.Haglund综合征开放手术治疗中的负重方案及结果:一项大型回顾性分析
Foot Ankle Orthop. 2025 Feb 17;10(1):24730114251316554. doi: 10.1177/24730114251316554. eCollection 2025 Jan.
7
The Frequency and Severity of Complications in Surgical Treatment of Osteochondral Lesions of the Talus: A Systematic Review and Meta-Analysis of 6,962 Lesions.距骨骨软骨病变手术治疗的并发症频率和严重程度:6962 个病灶的系统评价和荟萃分析。
Cartilage. 2023 Jun;14(2):180-197. doi: 10.1177/19476035231154746. Epub 2023 Mar 9.
Arthroscopic Microfracture for Osteochondral Lesions of the Talus: Functional Outcomes at a Mean of 6.7 Years in 165 Consecutive Ankles.
关节镜下微骨折术治疗距骨骨软骨病变:165 例连续踝关节平均 6.7 年的功能结果。
Am J Sports Med. 2020 Jan;48(1):153-158. doi: 10.1177/0363546519887957.
4
Current Status and Changes in Pain and Activities of Daily Living in Elderly Patients with Osteoarthritis Before and After Unilateral Total Knee Replacement Surgery.单侧全膝关节置换术前、后老年骨关节炎患者疼痛及日常生活活动能力的现状与变化
J Clin Med. 2019 Feb 8;8(2):221. doi: 10.3390/jcm8020221.
5
Patient compliance with touchdown weight bearing after microfracture treatment of talar osteochondral lesions.距骨骨软骨损伤微骨折治疗后患者对触地负重的依从性。
J Orthop Surg Res. 2017 Mar 20;12(1):46. doi: 10.1186/s13018-017-0548-5.
6
Clinical outcomes of early weight-bearing after arthroscopic microfracture during the treatment of osteochondral lesions of the talus.距骨骨软骨损伤治疗中关节镜下微骨折术后早期负重的临床结果
Chin Med J (Engl). 2014;127(13):2470-4.
7
Rehabilitation and return-to-sports activity after debridement and bone marrow stimulation of osteochondral talar defects.骨软骨距骨缺损清创和骨髓刺激后的康复和重返运动活动。
Sports Med. 2012 Oct 1;42(10):857-70. doi: 10.1007/BF03262299.
8
Outcome of arthroscopic debridement and microfracture as the primary treatment for osteochondral lesions of the talar dome.关节镜下清创术和微骨折术作为距骨穹窿骨软骨病变的主要治疗方法的结果。
Arthroscopy. 2012 Dec;28(12):1902-7. doi: 10.1016/j.arthro.2012.04.055. Epub 2012 Aug 11.
9
Comparison of early versus delayed weightbearing outcomes after microfracture for small to midsized osteochondral lesions of the talus.微骨折治疗距骨小至中型骨软骨病变后早期与延迟负重的疗效比较。
Am J Sports Med. 2012 Sep;40(9):2023-8. doi: 10.1177/0363546512455316. Epub 2012 Aug 9.
10
Effect of implantation accuracy on ankle contact mechanics with a metallic focal resurfacing implant.金属点状切除假体植入精度对踝关节接触力学的影响。
J Bone Joint Surg Am. 2010 Jun;92(6):1490-500. doi: 10.2106/JBJS.I.00431.