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十二指肠神经节细胞瘤:一种导致上消化道出血的罕见肿瘤。

Duodenal Ganglioneuroma: A Rare Tumor Causing Upper Gastrointestinal Bleed.

作者信息

Dhali Arkadeep, Ray Sukanta, Dhali Gopal Krishna, Ghosh Ranajoy, Sarkar Avik

机构信息

Department of GI Surgery, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal, India.

Department of Gastroenterology, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal, India.

出版信息

Surg J (N Y). 2021 Sep 14;7(3):e255-e258. doi: 10.1055/s-0041-1735644. eCollection 2021 Jul.

DOI:10.1055/s-0041-1735644
PMID:34541318
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8440055/
Abstract

Neuroblastic tumors (NTs) include neuroblastoma, ganglioneuroblastoma, and ganglioneuroma (GN). They are very rare in adults. The Surveillance, Epidemiology, and End Results identified 144 patients ≥20 years old at diagnosis (6.1%) from 1973 to 2002. GNs account for 14% of all localized NT. Since 1957, a total of four cases of GN of the duodenum have been reported. We report a novel case of GN of the periampullary region in the duodenum in a 41-year-old man presenting with chronic upper gastrointestinal bleed. Given the rarity of GNs in this age group and the nonspecificity of radiological features, this diagnosis is often missed until histopathology is done. This may negatively affect the prognosis of an otherwise well-prognosticated disease.

摘要

神经母细胞瘤(NTs)包括神经母细胞瘤、神经节神经母细胞瘤和神经节瘤(GN)。它们在成人中非常罕见。监测、流行病学和最终结果项目在1973年至2002年间确定了144例诊断时年龄≥20岁的患者(占6.1%)。神经节瘤占所有局限性神经母细胞瘤的14%。自1957年以来,共报告了4例十二指肠神经节瘤。我们报告了1例41岁男性十二指肠壶腹周围区域神经节瘤的新病例,该患者表现为慢性上消化道出血。鉴于该年龄组神经节瘤罕见且放射学特征不具特异性,在进行组织病理学检查之前,这种诊断常常被漏诊。这可能会对原本预后良好的疾病的预后产生负面影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c2/8440055/06969ba43004/10-1055-s-0041-1735644-i2100070cr-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c2/8440055/6850d68777a4/10-1055-s-0041-1735644-i2100070cr-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c2/8440055/b3d84a67fce5/10-1055-s-0041-1735644-i2100070cr-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c2/8440055/98fec76b4846/10-1055-s-0041-1735644-i2100070cr-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c2/8440055/d250c66de6e3/10-1055-s-0041-1735644-i2100070cr-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c2/8440055/a20db32dbc48/10-1055-s-0041-1735644-i2100070cr-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c2/8440055/06969ba43004/10-1055-s-0041-1735644-i2100070cr-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c2/8440055/6850d68777a4/10-1055-s-0041-1735644-i2100070cr-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c2/8440055/b3d84a67fce5/10-1055-s-0041-1735644-i2100070cr-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c2/8440055/98fec76b4846/10-1055-s-0041-1735644-i2100070cr-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c2/8440055/d250c66de6e3/10-1055-s-0041-1735644-i2100070cr-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c2/8440055/a20db32dbc48/10-1055-s-0041-1735644-i2100070cr-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c2/8440055/06969ba43004/10-1055-s-0041-1735644-i2100070cr-6.jpg

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本文引用的文献

1
Massive Upper Gastrointestinal Hemorrhage in Brunner's Gland Hamartoma of Duodenum.十二指肠Brunner腺错构瘤导致的大量上消化道出血
Cureus. 2021 Jun 23;13(6):e15875. doi: 10.7759/cureus.15875. eCollection 2021 Jun.
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Refractory hypoglycaemia in a localised gastrointestinal stromal tumour: Case report.局部胃肠道间质瘤伴难治性低血糖:病例报告
Int J Surg Case Rep. 2021 Jun;83:106023. doi: 10.1016/j.ijscr.2021.106023. Epub 2021 May 26.
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Treatment and outcome of Ganglioneuroma and Ganglioneuroblastoma intermixed.节细胞神经瘤与节细胞神经母细胞瘤混合型的治疗与预后
BMC Cancer. 2016 Jul 27;16:542. doi: 10.1186/s12885-016-2513-9.
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