Rosner-Tenerowicz Anna, Zimmer-Stelmach Aleksandra, Zimmer Mariusz
2nd Department of Gynecology and Obstetrics, Wroclaw Medical University.
Ginekol Pol. 2021 Sep 20. doi: 10.5603/GP.a2021.0140.
The aim of the study was to evaluate the effectiveness of CO₂ fractional laser therapy on perimenopausal urogenital symptoms.
This prospective, open-label study included 205 patients who received three CO₂ laser treatments. Clinical assessment was checked at baseline as well as at six weeks and 12 months post-treatment. The following scores were measured Vaginal Health Index Score (VHIS), International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) and assessment of the severity of selected urogenital symptoms.
Significant improvements in dryness, dyspareunia, burning, vaginal laxity, urinary incontinence, as were the results on the VHIS and ICIQ-UI SF at six weeks post-treatment (p < 0.05 for all scores), which were maintained through the follow-up visit at 12 months. No complications were observed either during or after laser therapy.
CO₂ ablative laser treatment can be effective in reducing vulvovaginal atrophy symptoms such as vaginal laxity, dryness, painful sexual intercourse, burning, and decreases the severity of stress urinary incontinence and urge incontinence symptoms. Positive results were maintained at 12 months after the laser treatment.
本研究旨在评估二氧化碳分次激光治疗对围绝经期泌尿生殖系统症状的有效性。
这项前瞻性、开放标签研究纳入了205例接受三次二氧化碳激光治疗的患者。在基线以及治疗后六周和12个月进行临床评估。测量以下评分：阴道健康指数评分（VHIS）、国际尿失禁咨询问卷-尿失禁简表（ICIQ-UI SF）以及对选定泌尿生殖系统症状严重程度的评估。
治疗后六周时，干燥、性交困难、烧灼感、阴道松弛、尿失禁等方面有显著改善，VHIS和ICIQ-UI SF评分结果也有显著改善（所有评分p<0.05），这些改善在12个月的随访中得以维持。激光治疗期间及之后均未观察到并发症。
二氧化碳剥脱性激光治疗可有效减轻外阴阴道萎缩症状，如阴道松弛、干燥、性交疼痛、烧灼感，并减轻压力性尿失禁和急迫性尿失禁症状的严重程度。激光治疗后12个月仍保持积极效果。
