Rossdales Equine Hospital, Newmarket, UK.
Fisher & Paykel Healthcare Limited, Maidenhead, Berkshire, UK.
Equine Vet J. 2022 Sep;54(5):946-951. doi: 10.1111/evj.13515. Epub 2021 Oct 13.
Respiratory disease is common in critically ill neonatal foals. Traditional oxygen therapy (TOT) with nasal insufflation of oxygen is often used to provide first-line respiratory support. Mechanical ventilation is used in foals which require a greater level of support but requires specialist expertise and can be associated with significant complications. Non-invasive ventilation (NIV) enables a greater level of respiratory support without the need for intubation. High flow oxygen therapy (HFOT) is a mode of NIV commonly used in human intensive care.
To describe the use of HFOT in hospitalised neonatal foals.
Retrospective case series.
Hospital records of neonatal foals admitted between 2018 and 2019 that received treatment with HFOT were reviewed. Clinical data and complications were recorded.
Fourteen foals were identified and the median duration of use was 43 hours (range 2-93 hours) with a median flow rate of 0.7L/kg/min (range 0.42-1.67). Ten foals survived to discharge. No significant complications associated with the technique were recorded.
A small study population which was retrospectively reviewed.
This study provides preliminary information about the clinical use of HFOT in neonatal foals. The technique was well tolerated and no significant adverse effects were noted. However, further study is required to evaluate efficacy.
呼吸疾病在重症新生儿驹中很常见。传统的氧气疗法(TOT)通过鼻内给氧常被用于提供一线呼吸支持。需要更高水平支持的驹则使用机械通气,但这需要专业知识,并且可能会伴随严重的并发症。无创通气(NIV)可以在无需插管的情况下提供更高水平的呼吸支持。高流量氧疗(HFOT)是一种在人类重症监护中常用的 NIV 模式。
描述 HFOT 在住院新生儿驹中的使用情况。
回顾性病例系列。
回顾了 2018 年至 2019 年期间接受 HFOT 治疗的住院新生儿驹的医院记录。记录了临床数据和并发症。
确定了 14 匹驹,中位使用时间为 43 小时(范围 2-93 小时),中位流速为 0.7L/kg/min(范围 0.42-1.67)。10 匹驹存活至出院。未记录到与该技术相关的重大并发症。
研究人群较小且为回顾性研究。
本研究提供了 HFOT 在新生儿驹中的临床使用的初步信息。该技术耐受性良好,未观察到明显的不良反应。然而,需要进一步的研究来评估其疗效。