Blaive B, Lemoigne F, Clary C, Bonnaud F
Service de Pneumologie Réanimation Respiratoire, CHU, Nice.
Allerg Immunol (Paris). 1987 Feb;19(2):61-4.
Intravenous administration of theophylline for acute asthmatic attacks treatment requires statistical adjustment of the dosage. In the absence of a residual level the former one is of 6 mg/kg for the loading dose and 0.6 mg/kg/h for the maintenance dose. In case of non estimated residual rate, it's possible either not to use the loading dose, or to use a reduced dosage of 3 mg/kg. In both cases, the maintenance dose is 0.7 mg/kg/h. In future, rapid theophylline dosage technics should allow a more appropriate adaptation in emergency treatment.
静脉注射茶碱用于治疗急性哮喘发作时需要对剂量进行统计学调整。在没有残留水平的情况下,前者的负荷剂量为6mg/kg,维持剂量为0.6mg/kg/小时。在未估计残留率的情况下,可以不使用负荷剂量,或者使用3mg/kg的减少剂量。在这两种情况下,维持剂量均为0.7mg/kg/小时。未来,快速的茶碱剂量技术应能在紧急治疗中实现更合适的调整。