参与嗜热四膜虫核糖体RNA自我剪接和RNA酶活性的结构。 - Suppr

Suppr

超能文献

Structures involved in Tetrahymena rRNA self-splicing and RNA enzyme activity.

作者信息

Been M D, Barfod E T, Burke J M, Price J V, Tanner N K, Zaug A J, Cech T R

机构信息

Department of Chemistry and Biochemistry, University of Colorado, Boulder 80309.

出版信息

Cold Spring Harb Symp Quant Biol. 1987;52:147-57. doi: 10.1101/sqb.1987.052.01.019.

DOI:10.1101/sqb.1987.052.01.019

PMID:3454258

Abstract

摘要

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Structures involved in Tetrahymena rRNA self-splicing and RNA enzyme activity.参与嗜热四膜虫核糖体RNA自我剪接和RNA酶活性的结构。

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Secondary structures of Tetrahymena thermophila rRNA IVS sequence involved in its self-splicing reactions: a new computer analysis.嗜热四膜虫rRNA IVS序列参与自身剪接反应的二级结构：一项新的计算机分析

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Identification of phosphate groups important to self-splicing of the Tetrahymena rRNA intron as determined by phosphorothioate substitution.通过硫代磷酸酯取代确定对嗜热四膜虫rRNA内含子自我剪接重要的磷酸基团。

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The intervening sequence RNA of Tetrahymena is an enzyme.嗜热四膜虫的间隔序列RNA是一种酶。

Science. 1986 Jan 31;231(4737):470-5. doi: 10.1126/science.3941911.

Deletion of nonconserved helices near the 3' end of the rRNA intron of Tetrahymena thermophila alters self-splicing but not core catalytic activity.嗜热四膜虫rRNA内含子3'端附近非保守螺旋的缺失会改变自我剪接，但不会改变核心催化活性。

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Specific interaction between the self-splicing RNA of Tetrahymena and its guanosine substrate: implications for biological catalysis by RNA.嗜热四膜虫自我剪接RNA与其鸟苷底物之间的特异性相互作用：对RNA生物催化的启示

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Mol Cell Biol. 1989 Sep;9(9):3657-66. doi: 10.1128/mcb.9.9.3657-3666.1989.

A conserved base pair within helix P4 of the Tetrahymena ribozyme helps to form the tertiary structure required for self-splicing.嗜热四膜虫核酶螺旋P4内的一个保守碱基对有助于形成自我剪接所需的三级结构。

EMBO J. 1989 Nov;8(11):3391-9. doi: 10.1002/j.1460-2075.1989.tb08503.x.

RNA structure, not sequence, determines the 5' splice-site specificity of a group I intron.RNA的结构而非序列决定了I类内含子的5'剪接位点特异性。

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EMBO J. 1990 Jun;9(6):1923-8. doi: 10.1002/j.1460-2075.1990.tb08319.x.

Characterization of the restriction site of a prokaryotic intron-encoded endonuclease.原核生物内含子编码的内切核酸酶限制位点的表征

Proc Natl Acad Sci U S A. 1990 May;87(9):3574-8. doi: 10.1073/pnas.87.9.3574.

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