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阿片类药物相关的副作用及处理。

Opioid-Related Side Effects and Management.

机构信息

UCLA Department of Anesthesiology and Perioperative Medicine, 757 Westwood Plaza #3325, Los Angeles, CA, 90095, USA.

UCLA Department of Anesthesiology and Perioperative Medicine, Los Angeles, CA, USA.

出版信息

Cancer Treat Res. 2021;182:97-105. doi: 10.1007/978-3-030-81526-4_7.

DOI:10.1007/978-3-030-81526-4_7
PMID:34542878
Abstract

The following areas will be discussed in relation to opioid-related side effects and approaches to their management in the cancer patient.

摘要

以下将讨论与阿片类药物相关的副作用及癌症患者管理这些副作用的方法。

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Opioid-Related Side Effects and Management.阿片类药物相关的副作用及处理。
Cancer Treat Res. 2021;182:97-105. doi: 10.1007/978-3-030-81526-4_7.
2
Recording and communicating opioid adverse drug reactions is an important element of opioid stewardship.记录和通报阿片类药物不良反应是阿片类药物管理的重要环节。
Intern Med J. 2023 Mar;53(3):454. doi: 10.1111/imj.16028.
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The cost of opioid-related adverse drug events.阿片类药物相关药品不良事件的成本。
J Pain Palliat Care Pharmacother. 2014 Sep;28(3):282-93. doi: 10.3109/15360288.2014.938889. Epub 2014 Aug 7.
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Adverse drug reactions of non-opioid and opioid analgesics reported to Croatian national authority from 2007 to 2014.2007年至2014年向克罗地亚国家当局报告的非阿片类和阿片类镇痛药的药物不良反应。
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Pain Management with Opioid Analgesics - How to Improve Efficacy, while Reducing Adverse Effects and Improve Patients' Quality of Life.阿片类镇痛药的疼痛管理——如何提高疗效、减少不良反应并改善患者生活质量。
Curr Pharm Des. 2019;25(30):3195-3196. doi: 10.2174/138161282530191010113245.
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Pain Med. 2015 Oct;16 Suppl 1:S1-2. doi: 10.1111/pme.12925. Epub 2015 Sep 9.
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Opioid prescriptions for chronic nonmalignant pain: driving on a dangerous road.用于慢性非恶性疼痛的阿片类药物处方:在危险道路上行驶。
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[Management of adverse effects of opioid therapy].[阿片类药物治疗的不良反应管理]
Z Gastroenterol. 2017 Apr;55(4):394-400. doi: 10.1055/s-0043-103348. Epub 2017 Mar 31.
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The prevalence and economic impact of prescription opioid-related side effects among patients with chronic noncancer pain.慢性非癌性疼痛患者中与处方阿片类药物相关副作用的患病率及经济影响。
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Long-term efficacy and reduced side-effects of buprenorphine in patients with moderate and severe chronic pain.丁丙诺啡对中重度慢性疼痛患者的长期疗效及副作用的减轻
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The Downregulation of Opioid Receptors and Neuropathic Pain.阿片受体下调与神经病理性疼痛。

本文引用的文献

1
The Management of Opioid-Induced Nausea and Vomiting in Patients with Cancer: A Systematic Review.癌症患者阿片类药物所致恶心和呕吐的管理:系统评价。
J Palliat Med. 2019 Jan;22(1):90-97. doi: 10.1089/jpm.2018.0260. Epub 2018 Sep 21.
2
Pharmacokinetic properties of intranasal and injectable formulations of naloxone for community use: a systematic review.社区使用的纳洛酮鼻内和注射制剂的药代动力学特性:一项系统评价。
Pain Manag. 2018 May;8(3):231-245. doi: 10.2217/pmt-2017-0060. Epub 2018 Apr 23.
3
Efficacy of Prophylactic Treatment for Oxycodone-Induced Nausea and Vomiting Among Patients with Cancer Pain (POINT): A Randomized, Placebo-Controlled, Double-Blind Trial.
Int J Mol Sci. 2023 Mar 22;24(6):5981. doi: 10.3390/ijms24065981.
4
Subanaesthetic single-dose ketamine as an adjunct to opioid analgesics for acute pain management in the emergency department: a systematic review and meta-analysis.亚麻醉剂量单次使用氯胺酮作为阿片类镇痛药辅助用于急诊科急性疼痛管理:系统评价和荟萃分析。
BMJ Open. 2023 Mar 27;13(3):e066444. doi: 10.1136/bmjopen-2022-066444.
预防性治疗癌症疼痛患者羟考酮所致恶心呕吐的疗效(POINT):一项随机、安慰剂对照、双盲试验。
Oncologist. 2018 Mar;23(3):367-374. doi: 10.1634/theoncologist.2017-0225. Epub 2017 Oct 16.
4
Efficacy of methylnaltrexone for the treatment of opiod-induced constipation: a meta-analysis and systematic review.甲基纳曲酮治疗阿片类药物所致便秘的疗效:一项荟萃分析与系统评价
Postgrad Med. 2016;128(3):282-9. doi: 10.1080/00325481.2016.1149017. Epub 2016 Feb 23.
5
Opioid-Induced Constipation.阿片类药物所致便秘
Pain Med. 2015 Oct;16 Suppl 1:S16-21. doi: 10.1111/pme.12911.
6
Use of naloxone for reversal of life-threatening opioid toxicity in cancer-related pain.纳洛酮用于逆转癌症相关疼痛中危及生命的阿片类药物毒性。
J Oncol Pharm Pract. 2016 Feb;22(1):114-20. doi: 10.1177/1078155214551589. Epub 2014 Sep 16.
7
Randomised clinical trial: the long-term safety and tolerability of naloxegol in patients with pain and opioid-induced constipation.随机临床试验:纳洛酮治疗疼痛和阿片类药物引起的便秘患者的长期安全性和耐受性。
Aliment Pharmacol Ther. 2014 Oct;40(7):771-9. doi: 10.1111/apt.12899. Epub 2014 Aug 12.
8
Mechanisms that underlie μ-opioid receptor agonist-induced constipation: differential involvement of μ-opioid receptor sites and responsible regions.μ 阿片受体激动剂引起便秘的机制:μ 阿片受体位点和责任区域的差异参与。
J Pharmacol Exp Ther. 2013 Oct;347(1):91-9. doi: 10.1124/jpet.113.204313. Epub 2013 Jul 31.
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Treatment of opioid-induced constipation: focus on the peripheral μ-opioid receptor antagonist methylnaltrexone.治疗阿片类药物引起的便秘:关注外周μ-阿片受体拮抗剂甲基纳曲酮。
Drugs. 2013 Aug;73(12):1297-306. doi: 10.1007/s40265-013-0084-5.
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Pharmacologic treatment of opioid-induced constipation.阿片类药物引起的便秘的药物治疗。
Expert Opin Investig Drugs. 2013 Oct;22(10):1225-7. doi: 10.1517/13543784.2013.819341. Epub 2013 Jul 9.