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利伯维尔大学中心医院产后出血:妇女的流行病学特征。

Primary postpartum haemorrhage at the Libreville University Hospital Centre: Epidemiological profile of women.

机构信息

University Hospital Centre of Libreville, Gynecology and Obstetric Service, Liberville, Gabon.

InterStates Centre for Higher Public Health Education in Central Africa (CIESPAC), Brazzaville, Congo.

出版信息

PLoS One. 2021 Sep 20;16(9):e0257544. doi: 10.1371/journal.pone.0257544. eCollection 2021.

Abstract

In Gabon, the proportion of maternal deaths directly related to Primary PostPartum Haemorrhage (PPPH) is 15 to 25%, despite the different means that the World Health Organization has made available to the providers of Emergency Obstetrical and Neonatal Care (EmONC). The objective of this study was to determine the prevalence and epidemiological characteristics of Primary PostPartum Haemorrhage to improve its management and reduce the rate of maternal deaths. An analytical retrospective study involved 42,728 records, whose data were collected using a chart collection form on the basis of information contained in partograms and other patient records. Sociodemographic variables were expressed using percentage. The relationship between the etiologies of PPPH and certain characteristics of the women was established using the ORs with their 95% confidence intervals. The difference was significant if p < 0.05. The prevalence of PPPH was 1.6%. Delivery haemorrhages accounted for 65.5% of PPPH. The main factors associated with delivery haemorrhages were pauci parity and multiparity (p = 0.003 and 0.051), post-term (p = 0.042), and birth weight >4,000 g (p = 0.006). Those associated with genital tract injuries were young maternal age (p = 0.008) and multiparity (p = 0.028). The most common etiology was haemorrhage from delivery. Multiparity remains the most common risk factor and the young age of the patients. It is important to improve management through better assessment of blood loss in the primary postpartum period as well as capacity building of health providers on EmONC.

摘要

在加蓬,与原发性产后出血(PPPH)直接相关的孕产妇死亡比例为 15%至 25%,尽管世界卫生组织为紧急产科和新生儿护理(EmONC)提供者提供了不同的手段。本研究的目的是确定原发性产后出血的流行率和流行病学特征,以改善其管理并降低孕产妇死亡率。一项分析性回顾性研究涉及 42728 份记录,使用图表收集表收集数据,该表基于产程图和其他患者记录中包含的信息。社会人口统计学变量用百分比表示。使用比值比(OR)及其 95%置信区间来确定 PPPH 的病因与妇女某些特征之间的关系。如果 p<0.05,则差异具有统计学意义。PPPH 的患病率为 1.6%。分娩出血占 PPPH 的 65.5%。与分娩出血相关的主要因素是多胎产次少(p=0.003 和 0.051)、过期妊娠(p=0.042)和出生体重>4000g(p=0.006)。与生殖道损伤相关的因素是产妇年龄较小(p=0.008)和多胎产次(p=0.028)。最常见的病因是分娩出血。多胎产次仍然是最常见的危险因素,且患者年龄较小。通过更好地评估初级产后期间的失血量以及对 EmONC 提供者进行能力建设,改善管理非常重要。

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本文引用的文献

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