Inorganic and Physical Chemistry Laboratory, Council of Scientific and Industrial Research (CSIR) - Central Leather Research Institute (CLRI), Adyar, Chennai, 600020, India.
Academy of Scientific and Innovative Research (AcSIR), New Delhi, India.
Curr Org Synth. 2022;19(3):366-392. doi: 10.2174/1570179418666210920150142.
Organoselenium chemistry has emerged as a distinctive area of research with tremendous utility in the synthesis of biologically and pharmaceutically active molecules. Significant synthetic approaches have been made for the construction of C-Se bonds, which are useful in other organic transformations. This review focuses on the versatility of transition metal-mediated selenylation reactions, providing insights into various synthetic pathways and mechanistic details. Furthermore, this review aims to offer a broad perspective for designing efficient and novel catalysts to incorporate organoselenium moiety into the inert C-H bonds.
有机硒化学已经成为一个独特的研究领域，在生物和药物活性分子的合成中具有巨大的应用价值。人们已经开发出了许多用于构建 C-Se 键的重要合成方法，这些方法在其他有机转化中也很有用。本文重点介绍了过渡金属介导的硒化反应的多功能性，深入探讨了各种合成途径和反应机理。此外，本文旨在为设计高效、新颖的催化剂提供广泛的视角，以将有机硒部分引入惰性的 C-H 键中。
