Wilcox J A, Nasrallah H A
Department of Psychiatry, University of Iowa, Iowa City.
Psychopathology. 1987;20(5-6):285-7. doi: 10.1159/000284512.
The medical histories of 30 paranoid schizophrenics were compared to those of 60 patients with nonparanoid schizophrenia. History of perinatal distress was more common in patients with chronic nonparanoid schizophrenia (p less than 0.005). A significant trend was noted for perinatal distress to be more common among cases with no family history of psychiatric illness (p less than 0.05). It is suggested that perinatal distress may be an organic risk factor for chronic nonparanoid schizophrenia and that this risk is independent of the genetic risk for this disease.
将30例偏执型精神分裂症患者的病史与60例非偏执型精神分裂症患者的病史进行了比较。围产期窘迫史在慢性非偏执型精神分裂症患者中更为常见（p<0.005）。在无精神疾病家族史的病例中，围产期窘迫更为常见，这一显著趋势被注意到（p<0.05）。有人提出，围产期窘迫可能是慢性非偏执型精神分裂症的一个器质性风险因素，而且这种风险独立于该疾病的遗传风险。
