Negri P, Agnello G, Borghesani F, Tomain L, Minisci N, D'Errico G, Cavallini A R
Istituto di Clinica Ostetrica e Ginecologica dell'Università degli Studi di Ferrara.
Acta Eur Fertil. 1987 Nov-Dec;18(6):375-80.
A triphasic oral contraceptive Trigynon (Schering) or Triphasil (Wyeth) was administered to 13 anovulatory women with hyperandrogenism, enlarged polycystic ovaries and reversal of LH/FSH ratio. After three months of treatment total Testosterone, Androstenedione and 17-OH-Progesterone levels significantly decreased while SHBG significantly increased. Reduction of hair growth and improvement of acne were noted. Side effects were minimal.
对13名患有高雄激素血症、多囊卵巢增大且LH/FSH比值倒置的无排卵女性给予三相口服避孕药Trigynon(先灵公司)或Triphasil(惠氏公司)。治疗三个月后,总睾酮、雄烯二酮和17-羟孕酮水平显著下降,而性激素结合球蛋白显著升高。观察到毛发生长减少和痤疮改善。副作用极小。