Northern Regional Health Administration, Cávado I - Braga Primary Healthcare Centres Group, Public Health Unit, Braga, Portugal.
Bioinformatics Unit, Department of Infectious Diseases, National Institute of Health Dr. Ricardo Jorge, Lisbon, Portugal.
Int J Infect Dis. 2021 Nov;112:318-320. doi: 10.1016/j.ijid.2021.09.035. Epub 2021 Sep 20.
Re-positivity of SARS-CoV-2 tests is widely reported, raising discussion about guidance for patient discharge and ending isolation. The unsuccessful recovery of replication-competent virus and/or absence of secondary cases has suggested that re-positive patients are not contagious. This study reports SARS-CoV-2 re-positivity in a healthcare professional 16 days after three negative tests, with viral genome sequencing supporting contagiousness leading to secondary cases.
SARS-CoV-2 检测的复阳现象被广泛报道，这引发了关于患者出院和隔离结束指导的讨论。未能成功恢复具有复制能力的病毒和/或没有二次感染病例表明，复阳患者没有传染性。本研究报告了一名医护人员在三次阴性检测后 16 天出现 SARS-CoV-2 复阳的情况，病毒基因组测序支持其具有传染性，导致了二次感染病例。
