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[Chinese guidelines for the diagnosis and treatment of adult acute myeloid leukemia (not APL) (2021)].《中国成人急性髓系白血病（非急性早幼粒细胞白血病）诊断与治疗指南（2021年版）》
Zhonghua Xue Ye Xue Za Zhi. 2021 Aug 14;42(8):617-623. doi: 10.3760/cma.j.issn.0253-2727.2021.08.001.
2
[Chinese guidelines for diagnosis and treatment of adult acute myeloid leukemia (not APL) (2023)].《成人急性髓系白血病（非急性早幼粒细胞白血病）诊断与治疗中国指南（2023年版）》
Zhonghua Xue Ye Xue Za Zhi. 2023 Sep 14;44(9):705-712. doi: 10.3760/cma.j.issn.0253-2727.2023.09.001.
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Radar plots facilitate differential diagnosis of acute promyelocytic leukemia and NPM1+ acute myeloid leukemia by flow cytometry.雷达图通过流式细胞术有助于急性早幼粒细胞白血病和 NPM1+ 急性髓系白血病的鉴别诊断。
Cytometry B Clin Cytom. 2021 Jul;100(4):409-420. doi: 10.1002/cyto.b.21979. Epub 2020 Dec 10.
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[Chinese guidelines for diagnosis and treatment of adult acute myeloid leukemia (not APL) (2017)].《成人急性髓系白血病（非急性早幼粒细胞白血病）诊断与治疗中国指南（2017年版）》
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Stepwise discriminant function analysis for rapid identification of acute promyelocytic leukemia from acute myeloid leukemia with multiparameter flow cytometry.运用多参数流式细胞术进行逐步判别函数分析以快速鉴别急性早幼粒细胞白血病与急性髓系白血病
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Acute myeloid leukemia with mutated NPM1 mimics acute promyelocytic leukemia presentation.伴突变型 NPM1 的急性髓系白血病模拟急性早幼粒细胞白血病表现。
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Acute myeloid leukemia with myelodysplasia-related changes mimicking acute promyelocytic leukemia.伴有骨髓增生异常相关改变的急性髓系白血病，酷似急性早幼粒细胞白血病。
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[Therapy-related myeloid neoplasms after successful treatment for acute promyelocytic leukemia: a report of four cases and literature review].急性早幼粒细胞白血病成功治疗后发生的治疗相关髓系肿瘤：4例报告及文献复习
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Influence on therapeutic outcome of platelet count at diagnosis in patients with de novo non-APL acute myeloid leukemia.初诊时血小板计数对非 APL 急性髓系白血病患者治疗结果的影响。
BMC Cancer. 2023 Oct 24;23(1):1030. doi: 10.1186/s12885-023-11543-5.
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Autologous hematopoietic cell transplantation for acute myeloid leukemia in adults: 25 years of experience in Japan.成人急性髓系白血病的自体造血细胞移植：日本 25 年的经验。
Int J Hematol. 2020 Jan;111(1):93-102. doi: 10.1007/s12185-019-02759-y. Epub 2019 Oct 14.

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HCQ reverses the immune imbalance related to severe infections following chemotherapy of acute myeloid leukemia and exhibits inhibitory effects on inflammatory cytokine storms.羟氯喹逆转急性髓系白血病化疗后与严重感染相关的免疫失衡，并对炎症细胞因子风暴具有抑制作用。
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[Comparison of the efficacy of continuous VA chemotherapy and I/HDAC consolidation in postremission therapy for acute myeloid leukemia fit for standard chemotherapy].[持续VA化疗与I/HDAC巩固在适合标准化疗的急性髓性白血病缓解后治疗中的疗效比较]
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Zhonghua Xue Ye Xue Za Zhi. 2025 Apr 14;46(4):336-342. doi: 10.3760/cma.j.cn121090-20240816-00305.
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The clinical features and outcomes of elderly patients with acute myeloid leukemia: a real word research.老年急性髓系白血病患者的临床特征与结局：一项真实世界研究
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Prognostic impact of mutations on acute myeloid leukemia.突变对急性髓系白血病的预后影响
Ther Adv Hematol. 2024 Sep 26;15:20406207241279533. doi: 10.1177/20406207241279533. eCollection 2024.
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[The clinical safety and efficacy of selinexor combined with venetoclax and azactitidine induction therapy in relapsed and refractory acute myeloid leukemia].塞利尼索联合维奈克拉及阿扎胞苷诱导治疗复发难治性急性髓系白血病的临床安全性与疗效
Zhonghua Xue Ye Xue Za Zhi. 2024 Aug 14;45(8):772-775. doi: 10.3760/cma.j.cn121090-20231031-00241.
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[Venetoclax combined with dose-reduced HAD as induction treatment for patients with de-novo acute myeloid leukemia].维奈托克联合减量的HAD方案作为初治急性髓系白血病患者的诱导治疗
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Treatment Patterns and Mutation Testing Among Patients with Acute Myeloid Leukemia in China: A Retrospective Observational Study.中国急性髓系白血病患者的治疗模式与突变检测：一项回顾性观察研究
Ther Clin Risk Manag. 2024 Feb 8;20:59-73. doi: 10.2147/TCRM.S434556. eCollection 2024.
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A case report of complete remission of acute myeloid leukemia combined with , and gene mutations and active pulmonary tuberculosis treated with homeharringtonine + venetoclax + azacytidine.高三尖杉酯碱+维奈克拉+阿扎胞苷治疗急性髓系白血病合并 、 及 基因突变及活动性肺结核完全缓解1例报告 （注：原文中“combined with”后面具体基因名称缺失）
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本文引用的文献

1
Oral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission.口服阿扎胞苷维持治疗急性髓系白血病缓解后。
N Engl J Med. 2020 Dec 24;383(26):2526-2537. doi: 10.1056/NEJMoa2004444.
2
Effect of rhG-CSF Combined With Decitabine Prophylaxis on Relapse of Patients With High-Risk MRD-Negative AML After HSCT: An Open-Label, Multicenter, Randomized Controlled Trial.rhG-CSF 联合地西他滨预防高危 MRD 阴性 AML 患者 HSCT 后复发的疗效：一项开放标签、多中心、随机对照试验。
J Clin Oncol. 2020 Dec 20;38(36):4249-4259. doi: 10.1200/JCO.19.03277. Epub 2020 Oct 27.
3
Benefit of intermediate-dose cytarabine containing induction in molecular subgroups of acute myeloid leukemia.含中剂量阿糖胞苷诱导治疗在急性髓系白血病分子亚组中的获益
Haematologica. 2020 Sep 28;106(5):1491-1495. doi: 10.3324/haematol.2020.267526.
4
Sorafenib maintenance in patients with FLT3-ITD acute myeloid leukaemia undergoing allogeneic haematopoietic stem-cell transplantation: an open-label, multicentre, randomised phase 3 trial.索拉非尼维持治疗伴 FLT3-ITD 急性髓系白血病行异基因造血干细胞移植患者：一项开放标签、多中心、随机 3 期临床试验。
Lancet Oncol. 2020 Sep;21(9):1201-1212. doi: 10.1016/S1470-2045(20)30455-1. Epub 2020 Aug 10.
5
Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia.阿扎胞苷和维奈托克治疗未经治急性髓系白血病。
N Engl J Med. 2020 Aug 13;383(7):617-629. doi: 10.1056/NEJMoa2012971.
6
Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With -Internal Tandem Duplication Mutation (SORMAIN).异基因造血干细胞移植治疗伴有内部串联重复突变的急性髓系白血病后的索拉非尼维持治疗（SORMAIN）。
J Clin Oncol. 2020 Sep 10;38(26):2993-3002. doi: 10.1200/JCO.19.03345. Epub 2020 Jul 16.
7
Randomized Trial of Intermediate-dose Cytarabine in Induction and Consolidation Therapy in Adults with Acute Myeloid Leukemia.随机临床试验：中剂量阿糖胞苷在成人急性髓细胞白血病诱导和巩固治疗中的应用。
Clin Cancer Res. 2020 Jul 1;26(13):3154-3161. doi: 10.1158/1078-0432.CCR-19-3433. Epub 2020 Feb 6.
8
Azacitidine maintenance after intensive chemotherapy improves DFS in older AML patients.强化化疗后阿扎胞苷维持治疗可改善老年 AML 患者的DFS。
Blood. 2019 Mar 28;133(13):1457-1464. doi: 10.1182/blood-2018-10-879866. Epub 2019 Jan 10.
9
Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia.维奈托克联合地西他滨或阿扎胞苷治疗初治老年急性髓系白血病患者。
Blood. 2019 Jan 3;133(1):7-17. doi: 10.1182/blood-2018-08-868752. Epub 2018 Oct 25.
10
Safety and preliminary efficacy of venetoclax with decitabine or azacitidine in elderly patients with previously untreated acute myeloid leukaemia: a non-randomised, open-label, phase 1b study.在未经治疗的老年急性髓系白血病患者中，venetoclax 联合地西他滨或阿扎胞苷的安全性和初步疗效：一项非随机、开放标签、1b 期研究。
Lancet Oncol. 2018 Feb;19(2):216-228. doi: 10.1016/S1470-2045(18)30010-X. Epub 2018 Jan 12.

[Chinese guidelines for the diagnosis and treatment of adult acute myeloid leukemia (not APL) (2021)].

出版信息

Zhonghua Xue Ye Xue Za Zhi. 2021 Aug 14;42(8):617-623. doi: 10.3760/cma.j.issn.0253-2727.2021.08.001.

DOI:10.3760/cma.j.issn.0253-2727.2021.08.001
PMID:34547865
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8501285/
Abstract
摘要