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乳腺隆乳术后隐匿性乳腺癌,彩色多谱勒超声未见低回声肿块样病变而诊断。

Hidden breast cancer after breast augmentation, not presenting as a hypoechoic mass lesion, diagnosed using colour Doppler ultrasound.

机构信息

Breast Oncology Service, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan

Breast Oncology Service, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.

出版信息

BMJ Case Rep. 2021 Sep 21;14(9):e242742. doi: 10.1136/bcr-2021-242742.

DOI:10.1136/bcr-2021-242742
PMID:34548294
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8458326/
Abstract

The main concern after breast augmentation with silicone injection is that silicone granulomas make it difficult to detect breast cancer. A case of breast cancer was diagnosed using colour Doppler ultrasound (CD) to detect an non-palpable mass not presenting as a hypoechoic mass lesion. An 83-year-old woman was incidentally found to have a lesion in her right breast, which was injected with silicone, showing 18F-fluorodeoxyglucose (FDG) uptake; the lesion was suspected to be breast cancer or silicone granuloma. A mass at the FDG uptake site was not detected on ultrasonography (US); however, observation using CD revealed a slightly hypoechoic area with hypervascularity. Core needle biopsy showed invasive ductal carcinoma. Patients in whom US does not reveal lesions after breast augmentation with silicone injection should undergo CD to detect hypervascularised tissue. To prevent false-negative biopsy results, CD is essential to detect cancer at suspected sites.

摘要

硅酮注射隆胸后主要关注的问题是硅酮肉芽肿使乳腺癌难以检出。我们通过彩色多谱勒超声(CD)检测到一个不可触及的肿块,该肿块未表现为低回声肿块病变,从而诊断出一例乳腺癌。一名 83 岁女性偶然发现右侧乳房有一个病变,该乳房曾被注入硅酮,18F-氟脱氧葡萄糖(FDG)摄取显示有摄取;病变被怀疑是乳腺癌或硅酮肉芽肿。超声(US)未发现 FDG 摄取部位有肿块;然而,CD 观察显示出一个稍低回声区,伴有丰富的血流。芯针活检显示为浸润性导管癌。硅酮注射隆胸后 US 未显示病变的患者应进行 CD 检查以检测富含血管的组织。为了防止活检结果出现假阴性,CD 对于检测可疑部位的癌症至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ace1/8458326/593bd9a4208c/bcr-2021-242742f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ace1/8458326/9ef2fb7ef1a1/bcr-2021-242742f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ace1/8458326/ac8833695ac6/bcr-2021-242742f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ace1/8458326/593bd9a4208c/bcr-2021-242742f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ace1/8458326/9ef2fb7ef1a1/bcr-2021-242742f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ace1/8458326/ac8833695ac6/bcr-2021-242742f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ace1/8458326/593bd9a4208c/bcr-2021-242742f03.jpg

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本文引用的文献

1
Bilateral Silicone Granulomas Mimicking Breast Cancer Recurrence on 18F-FDG PET/CT.双侧硅酮肉芽肿在 18F-FDG PET/CT 上模拟乳腺癌复发。
Clin Nucl Med. 2021 Feb 1;46(2):140-141. doi: 10.1097/RLU.0000000000003422.
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Multicenter Prospective Study of Color Doppler Ultrasound for Breast Masses: Utility of Our Color Doppler Method.彩色多普勒超声用于乳腺肿块的多中心前瞻性研究:我们的彩色多普勒方法的效用
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Breast carcinoma originating from a silicone granuloma: a case report.
起源于硅酮肉芽肿的乳腺癌:一例报告。
World J Surg Oncol. 2015 Feb 22;13:72. doi: 10.1186/s12957-015-0509-6.
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A false positive F-FDG PET/CT scan caused by breast silicone injection.乳房注射硅胶导致的 F-FDG PET/CT 扫描假阳性
Korean J Radiol. 2009 Mar-Apr;10(2):194-6. doi: 10.3348/kjr.2009.10.2.194. Epub 2009 Mar 3.
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Invasive micropapillary carcinomas arising 42 years after augmentation mammoplasty: a case report and literature review.隆乳术后42年发生的浸润性微乳头状癌:1例报告及文献复习
World J Surg Oncol. 2008 Mar 14;6:33. doi: 10.1186/1477-7819-6-33.
9
Sonographic and mammographic findings of breast liquid silicone injection.乳房液态硅胶注射的超声及乳房X线摄影表现
J Clin Ultrasound. 2006 Jul-Aug;34(6):273-7. doi: 10.1002/jcu.20235.
10
Sonographic features with histologic correlation in two cases of palpable breast cancer after breast augmentation by liquid silicone injection.两例注射液态硅胶隆乳术后可触及乳腺癌的超声特征与组织学相关性
J Clin Ultrasound. 2002 Nov-Dec;30(9):548-51. doi: 10.1002/jcu.10110.