Rubin J, Bryer J V, Brock-Utne J G, Moshal M G
S Afr Med J. 1977 Nov 12;52(21):835-7.
A prospective double-blind study of the effects of sedation in 142 patients undergoing gastro-intestinal endoscopy was performed. Four regimens were studied (neurolept analgesia with and without topical anaesthesia, and anticholinergic and topical anaesthesia, with and without diazepam). Droperidol and fentanyl without topical anaesthesia yielded the best results as far as tolerance and side-effects were concerned. It is suggested that this form of neurolept analgesia be used for gastro-intestinal endoscopy.
对142例接受胃肠内镜检查的患者进行了镇静效果的前瞻性双盲研究。研究了四种方案(有和没有局部麻醉的神经安定镇痛,以及抗胆碱能和局部麻醉,有和没有地西泮)。就耐受性和副作用而言,未使用局部麻醉的氟哌利多和芬太尼产生了最佳效果。建议将这种形式的神经安定镇痛用于胃肠内镜检查。