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2008-2013 年布基纳法索瓦加杜古医院收治的 5 岁以下儿童急性肠套叠:流行病学、临床和治疗方面。

Acute intestinal intussusception among children under five years of age admitted in an Ouagadougou hospital, Burkina Faso, 2008-2013: epidemiological, clinical and therapeutic aspects.

机构信息

Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle, Ouadougou, Burkina Faso.

Centers for Disease Control and Prevention, Atlanta, United States.

出版信息

Pan Afr Med J. 2021 Jul 28;39(Suppl 1):5. doi: 10.11604/pamj.supp.2021.39.1.25270. eCollection 2021.

DOI:10.11604/pamj.supp.2021.39.1.25270
PMID:34548897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8437429/
Abstract

INTRODUCTION

acute intestinal intussusception is a life-threatening surgical condition. In some settings, rotavirus vaccines have been associated with a low-level increased risk of intussusception. We describe the epidemiology, clinical manifestations and management of intussusception in a tertiary referral hospital in Burkina Faso prior to the introduction of rotavirus vaccine in October 2013.

METHODS

we retrospectively reviewed medical records of all children under 5 years of age treated at the Charles de Gaulle Pediatric Hospital for intussusception meeting the Brighton level 1 diagnostic criteria, from October 31st, 2008 to October 30th, 2013. We report the incidence of intussusception as well as descriptive characteristics of these cases.

RESULTS

a total of 107 Brighton level 1 intussusception cases were identified, representing a hospital incidence of 21.4 cases / year. There were 69 males and 38 females (sex ratio of 1.8), with a median age of 8 months (range 2 months to 4 years). Sixty-two percent of intussusception cases occurred among infants (n = 67 cases). The average time from symptom onset to seeking medical consultation was 3.8 days +/- 2.7 (range 0 to 14 days). Treatment was mainly surgical (105 patients, 98.1%) with 35 patients (32.7%) undergoing intestinal resection. Thirty-seven patients (35.5%) experienced post-operative complications. The mortality rate was 9.3%. Intestinal resection was a risk factor for death from intussusception.

CONCLUSION

in this review of intussusception hospitalizations prior to rotavirus vaccine introduction in Burkina Faso, delays in seeking care were common and were associated with mortality.

摘要

简介

急性肠套叠是一种危及生命的外科疾病。在某些情况下,轮状病毒疫苗与肠套叠的低水平风险增加有关。我们描述了 2013 年 10 月在布基纳法索引入轮状病毒疫苗之前,在一家三级转诊医院中肠套叠的流行病学、临床表现和治疗方法。

方法

我们回顾性地审查了 2008 年 10 月 31 日至 2013 年 10 月 30 日期间在戴高乐儿科医院因符合布莱顿 1 级诊断标准而接受肠套叠治疗的所有 5 岁以下儿童的病历。我们报告了肠套叠的发病率以及这些病例的描述性特征。

结果

共发现 107 例布莱顿 1 级肠套叠病例,占医院发病率的 21.4 例/年。男性 69 例,女性 38 例(性别比为 1.8),中位年龄为 8 个月(范围为 2 个月至 4 岁)。62%的肠套叠病例发生在婴儿(n=67 例)中。从症状出现到就诊的平均时间为 3.8 天±2.7(范围 0 至 14 天)。治疗主要是手术(105 例,98.1%),其中 35 例(32.7%)行肠切除术。37 例(35.5%)患者术后发生并发症。死亡率为 9.3%。肠切除术是肠套叠死亡的危险因素。

结论

在布基纳法索引入轮状病毒疫苗之前,对肠套叠住院患者的回顾性分析显示,寻求治疗的时间延迟很常见,并且与死亡率相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bb6/8437429/517c9257dbe1/PAMJ-SUPP-39-1-5-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bb6/8437429/a85f8cd69c38/PAMJ-SUPP-39-1-5-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bb6/8437429/7c5bd846eddb/PAMJ-SUPP-39-1-5-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bb6/8437429/517c9257dbe1/PAMJ-SUPP-39-1-5-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bb6/8437429/a85f8cd69c38/PAMJ-SUPP-39-1-5-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bb6/8437429/7c5bd846eddb/PAMJ-SUPP-39-1-5-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bb6/8437429/517c9257dbe1/PAMJ-SUPP-39-1-5-g003.jpg

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Preparing for safety monitoring after rotavirus vaccine implementation: a retrospective review of intussusception cases among children at a large teaching hospital in Rwanda, 2009-2012.准备轮状病毒疫苗实施后的安全性监测:2009-2012 年卢旺达一家大型教学医院中儿童肠套叠病例的回顾性研究。
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