Kort H I, Block B
S Afr Med J. 1977 Dec 31;52(28):1111-3.
The therapeutic use of synthetic luteinizing hormone-releasing hormone (LH-RH) to induce ovulation has been explored. Three dosage schemes have been compared: a single dose of LH-RH, multiple doses of LH-RH, and LH-RH used in combination with human menopausal gonadotrophins (HMG). The results of these three schemes are presented and compared; the last regimen has proved most successful, with a high pregnancy rate, a low incidence of multiple pregnancy and no evidence of ovarian hyperstimulation.
已对合成促黄体生成激素释放激素(LH-RH)诱导排卵的治疗用途进行了探索。比较了三种给药方案:单剂量LH-RH、多剂量LH-RH以及LH-RH与人绝经期促性腺激素(HMG)联合使用。展示并比较了这三种方案的结果;最后一种方案已被证明最为成功,妊娠率高、多胎妊娠发生率低且无卵巢过度刺激的迹象。