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丁型肝炎病毒感染:新西兰一种新近传入的疾病。

Hepatitis delta virus infection: a recently imported disease in New Zealand.

作者信息

Ramirez A M, Lee S P, Woodfield D G

机构信息

Auckland Regional Blood Centre.

出版信息

N Z Med J. 1987 Apr 22;100(822):235-7.

PMID:3454892
Abstract

In a study of 565 hepatitis B antigen (HBsAg) positive persons from the Auckland region, antibody to the hepatitis delta virus was detected in 38. The largest number were in Samoans (61%) although the infection was present in some other Pacific Islanders. Among HBsAg positive healthy blood donors, antenatal patients and acute hepatitis patients between 3.8 and 4.8% were anti-delta positive; while 28% of chronic hepatitis patients were positive suggesting an association between this disease and delta infection. Some positive results were also found in sera from intravenous drug addicts. By contrast, anti-delta was uncommon in New Zealand born Maoris or Europeans. Delta infection can be detected in some Pacific Islanders, some European immigrants as well as intravenous drug addicts and has the potential to spread in an epidemic form to HBsAg carriers in the general community. Widespread vaccination against hepatitis B is recommended to eventually reduce the number of HBsAg carriers in New Zealand.

摘要

在一项对奥克兰地区565名乙肝抗原(HBsAg)阳性者的研究中,检测到38人有丁型肝炎病毒抗体。人数最多的是萨摩亚人(61%),不过其他一些太平洋岛民中也存在这种感染。在HBsAg阳性的健康献血者、产前患者和急性肝炎患者中,3.8%至4.8%的人抗丁型肝炎病毒呈阳性;而28%的慢性肝炎患者呈阳性,这表明这种疾病与丁型肝炎感染之间存在关联。在静脉注射吸毒者的血清中也发现了一些阳性结果。相比之下,在新西兰出生的毛利人或欧洲人中,抗丁型肝炎病毒并不常见。在一些太平洋岛民、一些欧洲移民以及静脉注射吸毒者中可检测到丁型肝炎感染,并且有可能以流行形式传播给普通社区中的HBsAg携带者。建议广泛接种乙肝疫苗,以最终减少新西兰HBsAg携带者的数量。

相似文献

1
Hepatitis delta virus infection: a recently imported disease in New Zealand.丁型肝炎病毒感染:新西兰一种新近传入的疾病。
N Z Med J. 1987 Apr 22;100(822):235-7.
2
Prevalence of anti-delta antibodies in pregnant women in Bandung, Indonesia.印度尼西亚万隆孕妇中抗δ抗体的流行情况。
Trop Geogr Med. 1988 Jan;40(1):17-9.
3
Prevalence of delta antibodies among urban HBsAg-positive chronic liver disease patients in Egypt.埃及城市乙肝表面抗原阳性慢性肝病患者中δ抗体的流行率。
Hepatogastroenterology. 1988 Dec;35(6):313-5.
4
[Frequency and clinical relevance of delta virus infection in HBsAg carriers in the Berlin area].
Z Gastroenterol. 1988 Jun;26(6):314-21.
5
Delta hepatitis in Malaysia.马来西亚的丁型肝炎
Southeast Asian J Trop Med Public Health. 1986 Jun;17(2):229-33.
6
Anti-delta antibody in various HBsAg positive Argentine populations.阿根廷不同乙肝表面抗原阳性人群中的抗δ抗体。
Prog Clin Biol Res. 1987;234:517-8.
7
Hepatitis delta virus infection in Taiwan.台湾地区的丁型肝炎病毒感染
Prog Clin Biol Res. 1987;234:479-83.
8
[Prevalence of anti-delta antibodies in HBsAg carriers].
Mikrobiyol Bul. 1989 Apr;23(2):97-101.
9
[The intrahepatic expression of the hepatitis B virus in chronic delta hepatitis].[慢性丁型肝炎中乙型肝炎病毒的肝内表达]
Acta Med Port. 1993 May;6(5):187-91.
10
Delta infection in patients and HBsAg carriers.患者及乙肝表面抗原携带者中的德尔塔感染
Prog Clin Biol Res. 1987;234:461-6.

引用本文的文献

1
Delta hepatitis: molecular biology and clinical and epidemiological features.丁型肝炎:分子生物学及临床与流行病学特征
Clin Microbiol Rev. 1993 Jul;6(3):211-29. doi: 10.1128/CMR.6.3.211.