Sinniah M, Dimitrakakis M, Tan D S
Southeast Asian J Trop Med Public Health. 1986 Jun;17(2):229-33.
Sera from one hundred and fifty nine Malaysian individuals were screened for the prevalence of delta markers. These included 15 HBsAg positive homosexuals, 16 acute hepatitis B cases, 9 chronic hepatitis B patients, 13 healthy HBsAg carriers and 106 intravenous (i.v.) drug abusers, of whom 27 were positive for HBsAg only and the rest were anti-HBc IgG positive but HBsAg negative. The prevalence of delta markers in the homosexuals was found to be 6.7%, in the HBsAg positive drug abusers 17.8%, in acute hepatitis B cases 12.5%. No evidence of delta infection was detected in healthy HBsAg carriers, chronic hepatitis B cases and HBsAg negative i.v. drug abusers. With reference to i.v. drug abusers, the prevalence of delta markers was higher in Malays (23%) than in Chinese (7%) although the latter had a higher HBsAg carrier rate. Although the HBsAg carrier rate in the homosexuals was high, their delta prevalence rate was low as compared to drug abusers. In Malaysia, as in other non-endemic regions, hepatitis delta virus transmission appeared to occur mainly via the parenteral and sexual routes. This is the first time in Malaysia that a reservoir of delta infection has been demonstrated in certain groups of the population at high risk for hepatitis B.
对159名马来西亚人的血清进行了丁型肝炎标志物流行情况筛查。这些人包括15名HBsAg阳性同性恋者、16例急性乙型肝炎病例、9例慢性乙型肝炎患者、13名健康HBsAg携带者以及106名静脉注射吸毒者，其中27人仅HBsAg呈阳性，其余抗-HBc IgG呈阳性但HBsAg呈阴性。发现同性恋者中丁型肝炎标志物的流行率为6.7%，HBsAg阳性吸毒者中为17.8%，急性乙型肝炎病例中为12.5%。在健康HBsAg携带者、慢性乙型肝炎病例以及HBsAg阴性静脉注射吸毒者中未检测到丁型肝炎感染的证据。关于静脉注射吸毒者，马来人（23%）的丁型肝炎标志物流行率高于华人（7%），尽管华人的HBsAg携带率更高。虽然同性恋者的HBsAg携带率很高，但与吸毒者相比，他们的丁型肝炎流行率较低。在马来西亚，与其他非地方性流行地区一样，丁型肝炎病毒传播似乎主要通过肠道外和性途径发生。这是马来西亚首次在某些乙型肝炎高危人群中证实存在丁型肝炎感染源。
