Abbas Mahmoud, Pätzel Melanie, Thurn Angelika, Brinkmann Olaf Anselm, Bettendorf Olaf
Institute of Pathology and Cytology, D-48465 Schüttorf, Germany.
Urology Department, Bonifatius Hospital, D-49808 Lingen, Germany.
Mol Clin Oncol. 2021 Nov;15(5):223. doi: 10.3892/mco.2021.2386. Epub 2021 Aug 31.
Autosomal dominant polycystic kidney disease (ADPKD) is one of the best-known genetic diseases. Almost half of the patients with ADPKD will develop end-stage renal disease, and the majority of patients are treated with renal transplantation. The current study presents a case that developed papillary renal cell carcinoma (PRCC) in the native right kidney 10 years after renal transplantation. PRCC is a not common malignant tumour entity (18.5% of all cases of renal cell carcinoma) compared with common clear cell renal carcinoma (65-70% of all cases of RCC).
常染色体显性多囊肾病（ADPKD）是最广为人知的遗传性疾病之一。几乎一半的ADPKD患者会发展为终末期肾病，并且大多数患者接受肾移植治疗。当前的研究呈现了一个病例，该患者在肾移植10年后，其右侧原生肾发生了乳头状肾细胞癌（PRCC）。与常见的透明细胞肾细胞癌（占所有肾细胞癌病例的65 - 70%）相比，PRCC是一种不常见的恶性肿瘤实体（占所有肾细胞癌病例的18.5%）。
