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一名感染新冠病毒的儿童新发糖尿病:病例报告

New onset of diabetes in a child infected with COVID-19: a case report.

作者信息

Ordooei Mahtab, Behniafard Nasrin, Soheilipour Fahimeh, Akbarian Elahe

机构信息

Children Growth Disorder Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Department of Pediatrics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

出版信息

J Diabetes Metab Disord. 2021 Sep 17;20(2):2129-2132. doi: 10.1007/s40200-021-00900-5. eCollection 2021 Dec.

Abstract

BACKGROUND

Diabetic ketoacidosis (DKA) is a serious complication of type 1 diabetes. A few studies have reported that COVID-19 is associated with the development of new-onset diabetes. Here, we present an infected child with new onset diabetes leading to DKA.

CASE PRESENTATION

A 10-year-old patient with respiratory distress admitted to the Emergency Department of our center. The patient's COVID-19 Polymerase Chain Reaction (PCR) test was positive and also biochemical analyses confirmed that he had DKA. Despite standard initial treatments, ketoacidosis remained resistant; hence we prescribed oral bicarbonate (40 cc every 8 h) to treat the patient's refractory acidosis. Due to the patient's improvement, he was discharged after 10 days (7 days in the PICU), receiving outpatient enoxaparin (for a week) and ongoing subcutaneous insulin.

CONCLUSION

We report an interesting case of a child with COVID-19 infection precipitating presentation with new onset diabetes. Due to refractory acidosis, starting oral bicarbonate treatment after 2 days improved acidosis and tachypnea in the patient. The patient's medical team suggest close biochemical monitoring, prescribing enoxaparin for high level of D-dimer, and ordering oral bicarbonate acidosis persists.

摘要

背景

糖尿病酮症酸中毒(DKA)是1型糖尿病的一种严重并发症。一些研究报告称,2019冠状病毒病(COVID-19)与新发糖尿病的发生有关。在此,我们报告一名感染COVID-19后新发糖尿病并导致DKA的儿童病例。

病例介绍

一名10岁呼吸窘迫患者入住我院急诊科。患者的COVID-19聚合酶链反应(PCR)检测呈阳性,生化分析也证实他患有DKA。尽管进行了标准的初始治疗,但酮症酸中毒仍难以控制;因此,我们开具了口服碳酸氢盐(每8小时40毫升)来治疗患者的难治性酸中毒。由于患者病情好转,他在10天后(在儿科重症监护病房[PICU]住了7天)出院,接受门诊依诺肝素治疗(为期一周)并持续皮下注射胰岛素。

结论

我们报告了一例有趣的病例,一名感染COVID-19的儿童因新发糖尿病而就诊。由于难治性酸中毒,在2天后开始口服碳酸氢盐治疗改善了患者的酸中毒和呼吸急促症状。患者的医疗团队建议密切进行生化监测,对于D-二聚体水平升高的情况开具依诺肝素,并且在酸中毒持续存在时开具口服碳酸氢盐。

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New onset of diabetes in a child infected with COVID-19: a case report.一名感染新冠病毒的儿童新发糖尿病:病例报告
J Diabetes Metab Disord. 2021 Sep 17;20(2):2129-2132. doi: 10.1007/s40200-021-00900-5. eCollection 2021 Dec.

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