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鲁索替尼有效治疗一名8岁男孩的迟发性非感染性肺部并发症

Effective treatment of late-onset noninfectious pulmonary complication with ruxolitinib in an 8-year-old boy.

作者信息

Di Cicco Maria, Del Tufo Ester, Parolo Eva, Menconi Mariacristina, Bernasconi Sayla, Romei Chiara, Di Gangi Alessandro, Masini Beatrice, Peroni Diego, Casazza Gabriella

机构信息

Dept of Clinical and Experimental Medicine, Section of Pediatrics, University of Pisa, Pisa, Italy.

Pediatric Onco-haematology Unit, Pisa University Hospital, Pisa, Italy.

出版信息

ERJ Open Res. 2021 Sep 20;7(3). doi: 10.1183/23120541.00407-2021. eCollection 2021 Jul.

DOI:10.1183/23120541.00407-2021
PMID:34549045
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8450453/
Abstract

https://bit.ly/3BmOYfb.

摘要

https://bit.ly/3BmOYfb.（此为网址，无法准确翻译为中文，保留原文）

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Effective treatment of late-onset noninfectious pulmonary complication with ruxolitinib in an 8-year-old boy.鲁索替尼有效治疗一名8岁男孩的迟发性非感染性肺部并发症
ERJ Open Res. 2021 Sep 20;7(3). doi: 10.1183/23120541.00407-2021. eCollection 2021 Jul.
2
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本文引用的文献

1
FDA Approval Summary: Ruxolitinib for Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease.美国食品和药物管理局批准概要：芦可替尼治疗激素难治性急性移植物抗宿主病。
Oncologist. 2020 Feb;25(2):e328-e334. doi: 10.1634/theoncologist.2019-0627. Epub 2019 Oct 22.
2
Ruxolitinib is an effective steroid sparing agent in bronchiolitis obliterans due to chronic graft-versus-host-disease.芦可替尼是一种有效的、可减少类固醇用量的药物，用于治疗慢性移植物抗宿主病所致的闭塞性细支气管炎。
Bone Marrow Transplant. 2020 Jun;55(6):1194-1196. doi: 10.1038/s41409-019-0662-6. Epub 2019 Sep 4.
3
Ruxolitinib is an effective steroid sparing agent in children with steroid refractory/dependent bronchiolitis obliterans syndrome after allogenic hematopoietic cell transplantation.
芦可替尼对于异基因造血细胞移植后患有类固醇难治性/依赖性闭塞性细支气管炎综合征的儿童而言，是一种有效的类固醇节省剂。
Bone Marrow Transplant. 2019 Jul;54(7):1158-1160. doi: 10.1038/s41409-019-0450-3. Epub 2019 Jan 25.
4
Noninfectious lung complications after allogeneic haematopoietic stem cell transplantation.异基因造血干细胞移植后的非感染性肺部并发症。
Eur Respir J. 2018 May 3;51(5). doi: 10.1183/13993003.02617-2017. Print 2018 May.
5
Obliterative bronchiolitis.闭塞性细支气管炎
N Engl J Med. 2014 May 8;370(19):1820-8. doi: 10.1056/NEJMra1204664.
6
Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease.治疗性 JAK1/2 阻断在移植物抗宿主病中的活性。
Blood. 2014 Jun 12;123(24):3832-42. doi: 10.1182/blood-2013-12-543736. Epub 2014 Apr 7.
7
Diagnosis and treatment of pulmonary chronic GVHD: report from the consensus conference on clinical practice in chronic GVHD.肺慢性移植物抗宿主病的诊断与治疗：慢性移植物抗宿主病临床实践共识会议报告。
Bone Marrow Transplant. 2011 Oct;46(10):1283-95. doi: 10.1038/bmt.2011.35. Epub 2011 Mar 28.
8
Late-onset non-infectious pulmonary complications following allogeneic hematopoietic stem cell transplantation in children.儿童异基因造血干细胞移植后迟发性非感染性肺部并发症
Bone Marrow Transplant. 2009 Sep;44(5):303-8. doi: 10.1038/bmt.2009.33. Epub 2009 Apr 6.
9
Correlation of lung abnormalities on high-resolution CT with clinical graft-versus-host disease after allogeneic versus autologous bone marrow transplantation in children.儿童异基因与自体骨髓移植后高分辨率CT上肺部异常与临床移植物抗宿主病的相关性
Pediatr Radiol. 2008 Nov;38(11):1201-9. doi: 10.1007/s00247-008-0984-9. Epub 2008 Sep 4.
10
Interpretative strategies for lung function tests.肺功能测试的解读策略。
Eur Respir J. 2005 Nov;26(5):948-68. doi: 10.1183/09031936.05.00035205.