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免疫功能正常患者的复发性食管狭窄

Recurrent -Associated Esophageal Strictures in an Immunocompetent Patient.

作者信息

Narang Natasha, Pinillos Hugo, Amog-Jones Glenda, Gomez Adam, Alishahi Yasmin

机构信息

Department of Internal Medicine, University of Arizona College of Medicine, Phoenix, AZ.

Clinical Assistant Professor of Medicine, University of Arizona College of Medicine, Phoenix, AZ.

出版信息

ACG Case Rep J. 2021 May 19;8(5):e00603. doi: 10.14309/crj.0000000000000603. eCollection 2021 May.

DOI:10.14309/crj.0000000000000603
PMID:34549070
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8443842/
Abstract

Esophageal stricture due to esophagitis is a rare complication reported among immunocompromised patients in only limited case reports. We describe a unique case of a 36-year-old man with chronic mucocutaneous candidiasis without underlying immunocompromise who experienced over 10 years of recurrent dysphagia due to esophageal strictures from candidiasis. His symptoms were initially believed to be due to eosinophilic esophagitis; however, numerous biopsies from the esophagus were negative for eosinophils. Several upper endoscopies, however, did reveal fungal elements consistent with spp. He experienced recurring episodes of dysphagia and persistent esophageal stricture, requiring multiple antifungal courses and endoscopic balloon dilatations.

摘要

食管炎所致食管狭窄是一种罕见的并发症,仅在有限的病例报告中见于免疫功能低下的患者。我们描述了一例独特的病例,一名36岁男性患有慢性黏膜皮肤念珠菌病,但无潜在的免疫功能低下,因念珠菌病导致食管狭窄,经历了10多年的复发性吞咽困难。他的症状最初被认为是由于嗜酸性食管炎;然而,多次食管活检显示嗜酸性粒细胞阴性。然而,几次上消化道内镜检查确实发现了与念珠菌属一致的真菌成分。他经历了复发性吞咽困难发作和持续性食管狭窄,需要多次抗真菌治疗和内镜下球囊扩张。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/609b/8443842/b4b255e7a44c/ac9-8-e00603-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/609b/8443842/067f44c2e05b/ac9-8-e00603-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/609b/8443842/0b085d6db836/ac9-8-e00603-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/609b/8443842/9d0b9ba6dd8a/ac9-8-e00603-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/609b/8443842/b4b255e7a44c/ac9-8-e00603-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/609b/8443842/067f44c2e05b/ac9-8-e00603-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/609b/8443842/0b085d6db836/ac9-8-e00603-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/609b/8443842/9d0b9ba6dd8a/ac9-8-e00603-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/609b/8443842/b4b255e7a44c/ac9-8-e00603-g004.jpg

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