Shapiro B D, Ehrenpreis E D, Tomaka F L, Bonner G F, Secrest K M, Cheney L M
Department of Gastroenterology, Cleveland Clinic Florida, USA.
South Med J. 1997 Jan;90(1):80-2.
A number of disorders may result in the complaint of dysphagia in HIV-infected patients. These include fungal, viral, bacterial, parasitic, medication-induced, and idiopathic lesions in the esophagus. In the current case, a 32-year-old man with advanced HIV infection had recurrent bouts of esophageal stricture. No ulcer was associated with this stricture. No infectious causes of the stricture could be determined. The patient required multiple upper endoscopies and dilatations for treatment of this stricture and subsequently had a food impaction. This is the first case in the medical literature of an idiopathic stricture in the middle portion of the esophagus in an HIV-infected patient. We postulate that this lesion may have been caused by the patient's medications. Esophageal strictures should be considered in HIV-infected patients with severe dysphagia or food-bolus impactions of the esophagus.
许多病症可能导致HIV感染患者出现吞咽困难的症状。这些病症包括食管的真菌、病毒、细菌、寄生虫、药物性及特发性病变。在本病例中,一名32岁晚期HIV感染男性反复出现食管狭窄。此次狭窄未伴有溃疡。未能确定该狭窄的感染性病因。患者因该狭窄需要多次接受上消化道内镜检查及扩张治疗,随后出现食物嵌塞。这是医学文献中首例HIV感染患者食管中段特发性狭窄的病例。我们推测该病变可能由患者所服用的药物引起。对于有严重吞咽困难或食管食物团嵌塞的HIV感染患者,应考虑食管狭窄的可能。