Xing Daniel T, Yilmaz Helene, Hettige Supan, Hegde Rajendra, Nair Rohan
Oliver Newton-John Cancer Wellness and Research Centre, Austin Health, Melbourne, AUS.
Pathology, TissuPath, Melbourne, AUS.
Cureus. 2021 Aug 18;13(8):e17287. doi: 10.7759/cureus.17287. eCollection 2021 Aug.
Malignant priapism is a condition of painful induration and erection of the penis secondary to metastatic infiltration by a neoplasm. This condition is associated with a poor prognosis. We report on a case of an 87-year-old man who presented with a painful, partially erected penis subsequent to a diagnosis of metastatic Gleason 4+5 prostate cancer. Magnetic resonance imaging (MRI) showed diffuse bilateral infiltration of his corpora cavernosa. The core biopsy of the penile nodule revealed it to be a poorly differentiated carcinoma consistent with prostatic origin. The patient's symptoms were completely resolved after treatment with high-dose palliative conformal radiotherapy (40Gy in 16 fractions). We systemically reviewed clinical reports of palliative radiotherapy for malignant priapism with the aim to gain more information on the management of this rare condition.
恶性阴茎异常勃起是一种因肿瘤转移性浸润继发的阴茎疼痛性硬结和勃起状态。这种情况预后较差。我们报告一例87岁男性患者，在诊断为转移性Gleason 4+5前列腺癌后出现阴茎疼痛、部分勃起。磁共振成像（MRI）显示其双侧海绵体弥漫性浸润。阴茎结节的核心活检显示为低分化癌，与前列腺来源一致。患者经高剂量姑息性适形放疗（16次分割，共40Gy）治疗后症状完全缓解。我们系统回顾了恶性阴茎异常勃起姑息性放疗的临床报告，旨在获取更多关于这种罕见病症治疗的信息。
