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恶性阴茎异常勃起诊断与治疗中的当前挑战:全面综述

The Current Challenges in Diagnosing and Treating Malignant Priapism: A Comprehensive Review.

作者信息

Yudiana I Wayan, Sugianto Ronald, Putri Putu Eka Dianti, Ekawati Ni Putu, Duarsa Gede Wirya Kusuma

机构信息

Department of Urology, Universitas Udayana, Prof. Dr. I.G.N.G Ngoerah General Hospital, Faculty of Medicine, Bali, Indonesia.

Universitas Udayana, Medical Doctor Study Program, Faculty of Medicine, Bali, Indonesia.

出版信息

Urol Res Pract. 2023 Nov;49(6):360-364. doi: 10.5152/tud.2023.23088.

DOI:10.5152/tud.2023.23088
PMID:37971391
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10765201/
Abstract

Malignant priapism (MP) is defined as a condition of persistent erection of the penis without sexual stimulation due to the neoplastic process of the cavernous sinus and the efferent veins. The effectiveness of established therapeutic recommendations in priapism was ineffective in MP. Modalities of therapy for MP varied from medication treatment, nonsurgical treatment, surgical treatment, and radiotherapy. Despite aggressive surgical management combined with radiation therapy, chemotherapy, or targeted therapy, the survival rate remains low. Therefore, the treatment is usually palliative, focusing on the patient's quality of life improvement and symptom relief.

摘要

恶性阴茎异常勃起(MP)被定义为由于海绵体窦和输出静脉的肿瘤性病变,在无性刺激的情况下阴茎持续勃起的一种病症。已确立的阴茎异常勃起治疗建议对MP无效。MP的治疗方式包括药物治疗、非手术治疗、手术治疗和放射治疗。尽管采取了积极的手术治疗并结合放射治疗、化疗或靶向治疗,生存率仍然很低。因此,治疗通常是姑息性的,重点在于改善患者的生活质量和缓解症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad44/10765201/f20fc45ec0a4/urp-49-6-360_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad44/10765201/f20fc45ec0a4/urp-49-6-360_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad44/10765201/f20fc45ec0a4/urp-49-6-360_f001.jpg

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Successful Treatment of Malignant Priapism by Radiotherapy: Report of a Case, Review of the Literature, and Treatment Recommendations.放射治疗成功治疗恶性阴茎异常勃起:病例报告、文献综述及治疗建议
Cureus. 2021 Aug 18;13(8):e17287. doi: 10.7759/cureus.17287. eCollection 2021 Aug.
3
Penile gangrene: an unusual complication of malignant priapism in a patient with renal cell carcinoma.
阴茎坏疽:肾细胞癌患者恶性阴茎异常勃起的一种罕见并发症。
Pan Afr Med J. 2019 Nov 5;34:130. doi: 10.11604/pamj.2019.34.130.20447. eCollection 2019.
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Malignant priapism in metastatic adenocarcinoma of gastrointestinal origin: A F-FDG PET/CT study.转移性胃肠道来源腺癌所致恶性阴茎异常勃起:F-FDG PET/CT 研究。
J Med Imaging Radiat Oncol. 2021 Dec;65(7):904-906. doi: 10.1111/1754-9485.13163. Epub 2021 Feb 26.
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Malignant Priapism - What Do We Know About It?恶性阴茎异常勃起——我们对此了解多少?
In Vivo. 2020 Sep-Oct;34(5):2225-2232. doi: 10.21873/invivo.12033.
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Sex Med Rev. 2021 Apr;9(2):312-319. doi: 10.1016/j.sxmr.2019.11.002. Epub 2020 Jan 2.
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