Alcohol and Substance Treatment Center, Moodist Hospital, Istanbul, Turkey.
Department of Psychiatry, Van Research and Training Hospital, Van, Turkey.
J Psychoactive Drugs. 2022 Sep-Oct;54(4):358-367. doi: 10.1080/02791072.2021.1976887. Epub 2021 Sep 23.
Understanding the factors that lead to relapse is important for developing effective treatment strategies. The aim of this study is to examine sociodemographic and clinical factors that predict relapse 3 and 12 months after inpatient treatment in patients with alcohol and substance use disorders. 247 patients were included in the study. A sociodemographic data form and the Addiction Profile Index-Clinical Form (API-C) were filled out during the first days of hospitalization and relapse information was obtained through outpatient interviews. Logistic regression analysis was used to assess predictive factors. Rates of relapse for the 3 and 12 months were 40.5% and 74.6%, respectively. Motivation to quit substance use, risk of depression, being on probation, and being employed predicted relapse within the 3-month period. At the 12 month, substance use intensity and motivation to quit were the factors associated with relapse. To conclude, motivation to quit is critical to maintaining both early and sustained remission. Moreover, divergent factors may be relevant at different stages of treatment. Defining relapse predictors early in the process and being vigilant to the change in the needs of patients as the treatment continues may help to develop a more effective and focused treatment plan.
了解导致复发的因素对于制定有效的治疗策略很重要。本研究旨在探讨社会人口统计学和临床因素，以预测酒精和物质使用障碍患者住院治疗后 3 个月和 12 个月的复发情况。研究纳入了 247 名患者。在住院的头几天填写社会人口统计学数据表格和成瘾特征指数-临床表格（API-C），并通过门诊访谈获取复发信息。使用逻辑回归分析评估预测因素。3 个月和 12 个月的复发率分别为 40.5%和 74.6%。戒烟动机、抑郁风险、缓刑和就业预测了 3 个月内的复发。在 12 个月时，物质使用强度和戒烟动机是与复发相关的因素。总之，戒烟动机对于保持早期和持续缓解都很重要。此外，在治疗的不同阶段，可能存在不同的相关因素。在治疗过程的早期确定复发预测因素，并警惕患者需求的变化，可能有助于制定更有效和有针对性的治疗计划。
